Vice President / Senior Vice President, Clinical Development

Job Description

Job Description

Company Summary :  Korro is a biopharmaceutical company focused on developing a new class of genetic medicines for both rare and highly prevalent diseases using its proprietary RNA editing platform. Korro is generating a portfolio of differentiated programs that are designed to harness the body’s natural RNA editing process to effect a precise yet transient single base edit. By editing RNA instead of DNA, Korro is expanding the reach of genetic medicines by delivering additional precision and tunability, which has the potential for increased specificity and improved long-term tolerability. Using an oligonucleotide-based approach, Korro expects to bring its medicines to patients by leveraging its proprietary platform with precedented delivery modalities, manufacturing know-how, and established regulatory pathways of approved oligonucleotide drugs. Korro’s lead program is Alpha-1 Antitrypsin Deficiency (AATD). Korro is based in Cambridge, Massachusetts.

We are collaborative and united by a common mission. We are building a company with extraordinary people with an audacious vision to create transformative genetic medicines for prevalent diseases. Our values - Rewrite the future, On the Cutting Edge, Better Together, Dynamically Different, Kindness and Integrity form the fabric of the organization. They are reinforced daily and serve as key dimensions in the hiring process to help us ensure that Korro is a magnet for outstanding talent and a great place to work. Join us as we redefine what's possible in genetic medicine and work to make a lasting impact on human health.

Position Summary

We are seeking an exceptional VP (or SVP) of Clinical Development to lead our clinical strategy and oversee clinical trial execution across a diverse pipeline of RNA editing therapeutics. This role will be instrumental in advancing multiple programs from preclinical development through clinical proof-of-concept and beyond, working at the forefront of a transformative new therapeutic modality. Reporting to the Chief Scientific Officer, this position will work in close partnership with the VP of Clinical Operations, VP of Regulatory Affairs and VP Research & Preclinical to ensure seamless execution of Korro's preclinical and clinical development strategy. This role will have direct oversight of the Pharmacovigilance function.

Key Responsibilities :

Strategic Leadership :

• Define and execute clinical development strategy across Korro's portfolio spanning metabolic diseases, rare diseases, autoimmune conditions, and neurological disorders
• Partner with research, regulatory, and clinical operations to shape program priorities and accelerate paths to proof-of-concept
• Lead clinical planning for novel RNA editing programs, establishing precedents for this emerging therapeutic class
• Contribute to business development activities, including evaluation of external opportunities and partnership discussions

Clinical Strategy & Study Design :

Safety & Pharmacovigilance Leadership :

Cross-Functional Collaboration :

Medical & Scientific Leadership :

Team Leadership & Development :

Qualifications : Experience :

Technical Expertise :

Leadership & Strategic Skills :

Communication & Collaboration :

Preferred Qualifications :

Why Join Korro Bio :

Benefits :   Korro offers competitive compensation, including equity-based compensation, and a comprehensive benefits package that includes medical, dental, vision, 401(k) retirement plan, life insurance, a dependent care flexible spending account and a Company-funded health savings account and free parking.

We may use artificial intelligence (AI) tools to support parts of the hiring process, such as reviewing applications, analyzing resumes, or assessing responses. These tools assist our recruitment team but do not replace human judgment. Final hiring decisions are ultimately made by humans. If you would like more information about how your data is processed, please contact us.