Structural Immunology Faculty Search - Open Rank / Tenure-Track

The Ohio State University College of Medicine and the Wexner Medical Center seek a tenure-track faculty to join the Department of Biological Chemistry and Pharmacology and the Pelotonia Institute for Immuno-Oncology. Candidates at the rank of Associate Professor are preferred, but other ranks will be considered. Academic rank and track commensurate with academic record and experience.

Position Overview

The Department of Biological Chemistry and Pharmacology and the Pelotonia Institute for Immuno-Oncology (PIIO) at The Ohio State University invite applications for a tenure-track faculty to lead an independent research program focused structural biology and immuno-oncology with an emphasis on molecular mechanisms of immune regulation in cancer. The faculty would leverage OSUs cryo-EM, NMR, X-ray crystallography, and computational biology resources to study protein-protein and protein-ligand interactions in immune pathways. Candidates at the rank of Associate Professor are preferred, but other ranks will be considered. Academic rank of the successful candidate will be determined based on qualifications and experience, including demonstrated excellence in research, teaching, service, and leadership.

Duties and Responsibilities

Tenure faculty (regardless of rank) - persons with the titles of professor, associate professor, assistant professor, and instructor who serve on appointments totaling 50% or more service to the university and who are eligible for tenure or who have obtained tenure. Duties and responsibilities are assigned in accordance with the workload guidelines laid out in the pattern of administration of each faculty members tenure initiation unit (TIU) and, as appropriate, regional campus; obligations will include research, service and / or teaching or clinical practice. These faculty will have earned doctorate or other terminal degree in the relevant field of study or possession of equivalent experience.

Requirements

Applicants must have a Ph.D. and / or M.D. in biochemistry, immunology, molecular biology or an associated field with expertise in structural biology, immunology, and oncology; a strong record of high-impact publications and sustained extramural funding; and demonstrated success in interdisciplinary collaboration and mentoring.

Department / Division Overview

The Department of Biological Chemistry and Pharmacology is home to research and education focused on understanding the molecular mechanisms of fundamentally important life processes. The department is host to a broad range of research, education and service programs spanning across the basic and translational sciences (https : / / medicine.osu.edu / departments / bcpharm). The departments mission is to advance research and education in fundamental biochemical, pharmacological, and cellular processes that drive human health and disease. BCP offers access to world-class research facilities and fosters a highly collaborative environment for exploring molecular mechanisms and therapeutic interventions. Faculty members in BCP are leaders in applying structural, biochemical, and pharmacological approaches to solving complex biomedical challenges.

The PIIO is a comprehensive bench-to-bedside research initiative focused on harnessing the bodys immune system to fight cancer at all levels (https : / / cancer.osu.edu / piio). Led by founding director Zihai Li, MD, PhD, the PIIO builds upon a rich portfolio of active investigator-initiated IO clinical trials being conducted at the OSUCCC James. PIIO faculty conduct research in Systems and Translational IO. The PIIO is supported by our Immune Monitoring and Discovery Platform (IMDP), which provides comprehensive cell-based and molecule-based immunoassay services to support basic, translational, and clinical IO studies. The PIIOs Immuno-Oncology Informatics Group (IOIG) provides data analytics for flow and mass cytometry, bulk and single-cell RNA-Seq, spatial transcriptomics and imaging, neoantigen discovery, and more.

Ohio State is also home to the Native MS Guided Structural Biology Center (https : / / nativems.osu.edu / ), a state-of-the-art facility dedicated to advancing structural biology research. The center provides researchers with access to specialized mass spectrometry technologies, enabling detailed analyses of protein complexes, their interactions, and dynamics in native-like states. This resource complements OSUs existing structural biology infrastructure, offering unique capabilities for studying molecular mechanisms and therapeutic targets in cancer immunology and beyond.

How to Apply

To be considered, please submit your application through Workday. Application materials must include a cover letter, curriculum vitae, a statement of research (up to 3 pages), a teaching statement, and a list of 3 references. In the teaching statement, please outline your approach to teaching and learning and your goals and vision as an educator. Applications received by August 15, 2025 will receive priority consideration. All inquiries should be directed in confidence to Jessica Berner (Jessica.Berner@osumc.edu).

Faculty Defined

Clinical faculty (regardless of rank) - Persons with titles of assistant professor-clinical, associate professor-clinical and professor-clinical. These faculty will have earned a doctor of medicine (MD), doctorate (PhD) orother terminal degree in the relevant field. Clinical faculty members are not eligible for tenure and areappointed for terms of three to five years. They may be reappointed to successive terms. Their principal careerfocus is the delivery of exemplary clinical care, and may include teaching, and / or research.

Tenure-Track faculty (regardless of rank) - Persons with the titles of assistant professor, associate professor, orprofessor who are eligible for tenure or who have obtained tenure. These faculty will have earned a doctorate(PhD), Doctor of Medicine (MD) or other terminal degree in the relevant field of study. Their primary careerfocus centers on research, service, and teaching.Tenure-track faculty with MD or MD / PhD degrees may also beinvolved in clinical care.

Research Faculty (regardless of rank) - Persons with the titles of research assistant professor, research associateprofessor, or research professor. These faculty will have earned a doctorate(PhD) or other terminal degree inthe relevant field of study.Research faculty members are not eligible for tenure and areappointed for terms ofone to five years. Their principal careerfocus is research.

The Ohio State University College of Medicine

The Ohio State University College of Medicine, with more than 5,000 learners, is the only academic medical center in central Ohio. Ranked as the 28th Best Medical School Research, 40th Best Medical School Primary Care, it is known nationwide for curricular innovation, pioneering research, and outstanding patient care at The Ohio State University Wexner Medical Center. With more than 2,600 faculty members, the college comprises 20 clinical departments, eight basic science departments and a School of Health and Rehabilitation Sciences.

The Wexner Medical Center

The Ohio State University Wexner Medical Center consists of The Ohio State University Health System, the College of Medicine, the Health Sciences Library and the Faculty Group Practice. The Ohio State Wexner Medical Center is committed to providing world-class care. At the Ohio State Wexner Medical Center, we're proud to be celebrating our 31st consecutive year ranked in the U.S. News amp; World Report Best Hospitals list. This year, the Ohio State Wexner Medical Center has 10 nationally ranked specialties out of 15 and two selected as high performing. U.S. News amp; World Report consistently ranks the Ohio State Wexner Medical Center as the top hospital in Columbus. The Wexner Medical Center is rated as high performing in 14 out of 20 common procedures and conditions, including abdominal aortic aneurysm repair, aortic valve surgery, heart attack, heart bypass surgery and heart failure.

The University

Eligible Ohio State employees receive comprehensive benefits packages, including medical, dental and vision insurance, tuition assistance for employees and their dependents, and state or alternative retirement options with competitive employer contributions.

Ohio State is a dynamic community where opportunity thrives, and individuals transform themselves and their world. Positions are available in countless fields and specialties. Become a Buckeye and contribute to an incredible legacy that serves to guide our future and shape a better tomorrow.

The Ohio State University is committed to enhancing academic excellence. Recruiting, supporting, and retaining faculty of the highest caliber is a core component of this commitment. The Office of Academic Affairs (OAA) has established Dual Careers and Faculty Relocation (DCFR) to focus on supporting new and prospective faculty and their loved ones. Service offerings include dual careers partner consultations, identifying potential employers and / or employment opportunities, consultation and resources related to relocation, as well as identifying opportunities to engage on campus and in the surrounding community. While employment opportunities are not guaranteed, resources and consultation are provided to support the partners of new and prospective faculty as they are considering or transitioning to The Ohio State University.

In addition to being responsive to dual-career opportunities, we strongly promote work-life balance to support our community members through a suite of institutionalized policies. Ohio State is an NSF ADVANCE institution and a member of the Ohio / Western Pennsylvania / West Virginia Higher Education Recruitment Consortium (HERC) .

Columbus, Ohio

The area offers a wide range of affordable housing, many cultural and recreational opportunities, excellent schools, and a strong economy based on government as well as service, transportation, and technology industries . Additional information about the Columbus area is available here . In addition to its Columbus campus, Ohio State has four regional campuses including Ohio State Lima, Ohio State Mansfield, Ohio State Marion, and Ohio State Newark, in addition to Ohio State ATI in Wooster.

The university is an equal opportunity employer, including veterans and disability.