Scientist

Amber Bio is a biotechnology company pioneering new gene editing modalities using multi-kilobase edits to reach previously undruggable patient populations. Founded by pioneers in the CRISPR field from leading institutions for gene editing research, the company is developing a first-of-its-kind RNA writing platform that can correct thousands of bases at once, thereby correcting genetic mutations safely and reversibly. Multiple openings are available on a rapidly growing team. If you are interested in building a new frontier in genetic medicine, please apply via LinkedIn.

Job Description : Scientist (Bioarchitect)

Position Overview :

The Scientist will play a pivotal role in bringing newly identified targets from concept to pipeline nomination and beyond, including design and experimental execution of proof-of-concept studies to support RNA editing programs. The ideal candidate will be responsible for identifying and onboarding disease-appropriate models, defining critical disease-relevant endpoints, and designing and executing experiments to evaluate novel lead therapeutics. This role will also include advancing lead molecules through optimization and candidate selection. Reporting into the VP of Development, the candidate will work at the interface of the Platform and Development teams to ensure the seamless transition of potential therapeutics from concept to preclinical testing.

Key Responsibilities :

Experimentation and Execution :

• Onboard and validate relevant cellular models, including iPSC-derived neuronal cells, to evaluate potential therapeutics in CNS and other disease areas
• Develop or source robust, disease-relevant endpoint assays for target validation and phenotypic assessment
• Design, initiate, and manage studies conducted at external CROs or academic institutions
• Analyze cells and tissues to support progression from hit discovery through lead optimization to candidate nomination

Data Analysis, Documentation, and Reporting :

Collaboration and Communication :

Qualifications :

Preference will be given to those who display :

If you have a passion for advancing gene editing technologies and desire to be part of a pioneering biotech company, we encourage you to apply and join our ambitious team.

Please apply directly through LinkedIn.

Amber Bio is an equal-opportunity employer and encourages applications from candidates of diverse backgrounds. We value diversity and are committed to creating an inclusive and supportive work environment for all employees.