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Principal Automation Engineer

Principal Automation Engineer

JobotLaguna Beach, CA, US
17 days ago
Job type
  • Full-time
Job description

Ready to shape the next generation of clinical automation? Join a mission-driven team where your innovations directly impact patient care and scientific breakthroughs. This is more than a job—it’s a chance to engineer solutions that save lives.

This Jobot Job is hosted by : Brendan Thomas

Are you a fit? Easy Apply now by clicking the "Apply Now" button and sending us your resume.

Salary : $130,000 - $200,000 per year

A bit about us :

Are you ready to take your automation expertise to the next level? We’re seeking a Principal Automation Engineer to lead groundbreaking innovation in clinical laboratory automation. This is your chance to design and implement cutting-edge solutions that directly accelerate advancements in patient care.

At our company, you won’t just be another engineer, you’ll be part of a mission-driven team that is transforming the way life, changing diagnostics are delivered. Here, your work doesn’t just improve processes, it improves lives.

Why join us?

  • Purpose-Driven Work : Every project you touch will help improve patient outcomes and advance the fight against cancer and other critical diseases.
  • Career Growth : We invest in our people with career coaching, leadership development, and extensive training opportunities.
  • Comprehensive Benefits : Competitive health plans (HMO & PPO), 401(k) with company match, Employee Stock Purchase Program, tuition reimbursement, generous PTO (16+ days plus holidays), and wellness resources.
  • Collaborative Culture : Join a team that values innovation, teamwork, and continuous learning in a fast-paced, world-class environment.

Job Details

As the Principal Automation Engineer, you’ll be at the forefront of designing, building, and optimizing automation for high-throughput clinical workflows. You will :

  • Engineer Next-Gen Workflows : Develop and implement automated solutions on advanced liquid handlers to support DNA / RNA extraction, Next-Gen Sequencing (NGS) library prep, and other molecular processes.
  • Innovate Across Teams : Partner with R&D, operations, and IT to create high-accuracy, scalable workflows that improve throughput and reliability.
  • Drive Integration : Connect automation platforms with Laboratory Information Management Systems (LIMS), ensuring seamless and secure data flow across multiple labs.
  • Advance Clinical Excellence : Contribute to assay development, validation plans, SOPs, and quality documentation to meet CAP / CLIA requirements.
  • Continuously Improve : Lead iterative design, testing, and refinement of automation workflows to enhance efficiency and reduce variability.
  • Be the Expert : Troubleshoot, optimize, and ensure long-term reliability of automated systems while mentoring peers and supporting multi-site deployments.
  • What You Bring

  • Bachelor’s degree in biology, engineering, biotechnology, or related field
  • 7+ years of experience developing automated molecular workflows on Hamilton or similar liquid handlers
  • Hands-on experience in CAP / CLIA-regulated laboratories
  • Strong background in molecular biology techniques, laboratory-developed tests (LDTs), or in vitro diagnostics (IVDs)
  • Proven success collaborating across R&D, clinical, and operations teams to deliver innovative solutions
  • Data-driven mindset, excellent problem-solving skills, and ability to thrive in a dynamic environment
  • Interested in hearing more? Easy Apply now by clicking the "Apply Now" button.

    Jobot is an Equal Opportunity Employer. We provide an inclusive work environment that celebrates diversity and all qualified candidates receive consideration for employment without regard to race, color, sex, sexual orientation, gender identity, religion, national origin, age (40 and over), disability, military status, genetic information or any other basis protected by applicable federal, state, or local laws. Jobot also prohibits harassment of applicants or employees based on any of these protected categories. It is Jobot’s policy to comply with all applicable federal, state and local laws respecting consideration of unemployment status in making hiring decisions.

    Sometimes Jobot is required to perform background checks with your authorization. Jobot will consider qualified candidates with criminal histories in a manner consistent with any applicable federal, state, or local law regarding criminal backgrounds, including but not limited to the Los Angeles Fair Chance Initiative for Hiring and the San Francisco Fair Chance Ordinance.

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    Automation Engineer • Laguna Beach, CA, US

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