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Biologist
BiologistIntegrated Resources, Inc ( IRI ) • Boston, Massachusetts, United States
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Biologist

Biologist

Integrated Resources, Inc ( IRI ) • Boston, Massachusetts, United States
1 day ago
Job type
  • Full-time
Job description

About the Company

The in vivo pharmacology Biologist will participate in the Gene Therapy in vivo pharmacology lab to execute experiments in support of the discovery and optimization of Client therapeutic candidates for genetic medicines.

About the Role

Work with team leads to design and execute in vivo pharmacology experiments to characterize activity, distribution, and clearance of genetic medicines in rodent models, including immunocompromised animals.

Responsibilities

  • Assist in the development and characterization of Client in vivo models.
  • Collaborate with cross-functional partners (Preclinical, toxicology, PK / PD modelling) to ensure the translation from discovery to development.
  • Provide written and verbal communication of work in study reports and team meetings.
  • Keep and maintain accurate and timely documentation of all practical work : completion of electronic notebook in alignment with Client procedure quality standards and Good Documentation Practices.
  • Ensure compliance with all health and safety regulations.

Qualifications

  • B.S / MS in life sciences (e.g., biology, neuroscience, or related field) or 2+ years’ experience working in pharmaceutical industry or contract research organization.
  • Required Skills

  • Passion, knowledge and experience in neuroscience or rare disease research.
  • Hands on experience of rodent handling and dosing, including but not limited to subcutaneous (SC), intravenous (IV) and intraperitoneal (IP).
  • Experience of small animal stereotaxic surgeries including but not limited to intracerebral (IC), intracisterna magna (ICM) and intracerebroventricular (ICV) injections in rodents will be a plus.
  • Experience of gross necropsies, tissue dissection, trimming and processing, collecting bodily fluids (blood, cerebrospinal fluid [CSF]).
  • Ability to adapt and exercise flexibility for changing platform needs, workflows and projects.
  • Ability to craft, complete and interpret experiments independently, and to advance scientific understanding.
  • Excellent communication skills and effective in collaborating across functional boundaries and in team environment.
  • Strong organization skills, attention to detail, critical thinking, multitasking, desire to learn new techniques and contribute to innovative projects in a fast-paced working environment.
  • Experience in processing, organizing, analyzing and visualizing data and information from disparate sources and ability to extract insight from data.
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