Associate Scientist, Postdoctoral Fellow - Electron Microscopy-based Polyclonal Epitope...

Job Description

Postdoctoral Research Fellow – Electron Microscopy-based Polyclonal Epitope Mapping Research Fellow in the Analytical Research & Development Department

Be a part of the legacy : Postdoctoral Research Fellow Program

Our Research Laboratories’ Postdoctoral Research Fellow Program aims to be a best-in-industry program for industrial postdoctoral researchers, designed to provide an academic focus in a commercial environment. With the resources, reach, and expertise of a large pharmaceutical company, postdoctoral researchers will be positioned to excel in an institution committed to breakthrough innovation in research and discovery.

Position Overview

We are seeking a highly motivated postdoctoral research fellow to join the Analytical Research & Development Department, in collaboration with the Protein Structural Chemistry Department at our company. The successful candidate will initiate an independent research project focused on developing and applying the innovative approach of polyclonal epitope mapping. The goal of this work is to deepen our understanding of mechanisms underlying immune protection and vaccine efficacy. This position offers broad opportunities for collaborations across our company, ranging from antigen / antibody characterization and preparation to structural elucidation, and polyclonal epitope mapping.

The research will contribute to advancing vaccine understanding and data-driven decision-making in vaccine design. The expectation is that this work will enhance the current knowledge of how an immune system interacts with a vaccine antigen to elicit protection, enabling rational vaccine optimization. This approach is aimed to ultimately impact our company’s pipeline of vaccine development, as well as the scientific community by yielding publications in high-tier scientific journals.

Responsibilities include but are not limited to

• Design, plan, and prepare antigen / antibody constructs to enable structural determination.
• Purify polyclonal antibodies or Fabs from sera and optimize complex formation for structural studies.
• Prepare and optimize cryo-EM grids and perform data collection and processing to elucidate the polyclonal antibody response.
• Collaborate with internal and external partners to design and execute experiments, analyze results, and interpret data.
• Communicate results clearly with colleagues and the external scientific community through presentations and publications in leading peer-reviewed journals.

Education Minimum Requirement

Candidates must currently hold a PhD or Ph.D. completed within 6 months of hire in Chemistry, Biology, Biochemistry, Structural Biology, Physics, Material Science, Pharmaceutical Science or related discipline.

Required Experience and Skills

Preferred Experience and Skills

Salary

Expected salary range : $75,000.00 – $86,000.00.

Benefits

Available benefits include bonus eligibility, health care and other insurance benefits (for employee and family), retirement benefits, paid holidays, vacation, and sick days. For Washington State Jobs, a summary of benefits is listed here.

Required Skills

Accountability, Adaptability, Analytical Chemistry, Bacteriology, Biolayer Interferometry, Cell Culture Techniques, Clinical Immunology, Computational Biology, Data Analysis, Immunoassays, Immunochemistry, In Vivo Mouse Models, Materials Science, Mathematical Biology, Microbiology, Microscopies, Molecular Biology, Parasitology, Polyclonal Antibody Production, Programming Languages, Scientific Research, Scientific Writing, siRNA Knockdown, Statistical Analysis.

Preferred Skills

Current Employees apply HERE.

EEO Statement

As an Equal Employment Opportunity Employer, we provide equal opportunities to all employees and applicants for employment and prohibit discrimination on the basis of race, color, age, religion, sex, sexual orientation, gender identity, national origin, protected veteran status, disability status, or other applicable legally protected characteristics. As a federal contractor, we comply with all affirmative action requirements for protected veterans and individuals with disabilities. For more information about personal rights under the U.S. Equal Opportunity Employment laws, visit : EEOC Know Your Rights, EEOC GINA Supplement.

Hybrid Work Model

Effective September 5, 2023, employees in office-based positions in the U.S. will be working a Hybrid work consisting of three total days on-site per week, Monday - Thursday, although the specific days may vary by site or organization, with Friday designated as a remote-working day, unless business critical tasks require an on-site presence. This Hybrid work model does not apply to, and daily in-person attendance is required for, field-based positions; facility-based, manufacturing-based, or research-based positions where the work to be performed is located at a Company site; positions covered by a collective-bargaining agreement (unless the agreement provides for hybrid work); or any other position for which the Company has determined the job requirements cannot be reasonably met working remotely. Please note, this Hybrid work model guidance also does not apply to roles that have been designated as "remote".

Location and Status

Employee Status : Regular. Relocation : Domestic. VISA Sponsorship : Yes. Travel Requirements : 10%.

Job Posting End Date

11 / 26 / 2025. A job posting is effective until 11 : 59 : 59 PM on the day BEFORE the listed job posting end date. Please ensure you apply to a job posting no later than the day BEFORE the job posting end date.

Requisition ID

R371711.

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