PK/PD Modeling / Pharmacometrics LeadMercor • Fond du Lac, Wisconsin, US
No longer accepting applications
PK / PD Modeling / Pharmacometrics Lead
Mercor • Fond du Lac, Wisconsin, US
1 day ago
Job type
- Part-time
- Remote
Job descriptionWho we’re looking for Deep hands-on experience in PK, PD, exposure–response modeling , and ideally population PK or QSP . - Expert at model fitting, sensitivity analysis, and identifying non-plausible parameter spaces. - Can evaluate the validity of dose–exposure predictions and detect high-risk extrapolations. - Comfortable designing model evaluation rubrics that distinguish between acceptable vs. non-credible outputs. - Able to articulate how quantitative checks should complement narrative decision logic. Nice-to-have : Experience supporting translational or clinical pharmacology leads in dose justification. - Familiarity with integrating nonclinical PK / PD data (2-species GLP → human FIH extrapolation). ### Experience level ~8–12 years of quantitative pharmacology experience in pharma, CROs, or modeling consultancies . - Strong portfolio in population PK / PD exposure–response , and parameter estimation using NONMEM, Monolix, or equivalent tools. - Demonstrated ability to interpret model results for decision-making, not just fit data. - Can create fit-for-purpose models and critique model structures or assumptions under uncertainty. ### Expectations Design and refine micro-evaluations for PK / PD performance (curve fits, parameter checks, error taxonomies). - Encode quantitative sanity checks into model rubrics for automated evaluation. - Define failure conditions (e.g., unsafe extrapolation, poor coverage curves, invalid assumptions). Inputs we give : PK / PD datasets, tox summaries, and performance prompts (e.g., “fit exposure–response curves, interpret safety margins”). - Example model outputs from automated systems. Expected outputs : Quantitative Rubrics : clear thresholds for acceptable parameter fits, coverage curve quality, and model integrity checks. - Golden Fit Examples : representative “ideal” PK / PD model outputs and visualizations for calibration. - Error Taxonomy : structured list of typical modeling or fitting errors, with root-cause annotations. - Meta-Layer Commentary : short note per rubric capturing how expert modelers recognize implausible or unsafe fits beyond numeric error values. ### Engagement Model & Compensation Contract / part-time , remote, outcome-based deliverables.
This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in
- quantitative structure and parameter plausibility
###
Create a job alert for this search
Modeling • Fond du Lac, Wisconsin, US
Related jobs
Enhance Rehabilitation is currently seeking qualified Physical Therapists candidates to join our dynamic team.As an Enhance Rehabilitation Physical Therapist, you will be a part of growing team pro...Show more
Fusion Medical Staffing-Therapy is seeking a travel Physical Therapist for a travel job in Fond du Lac, Wisconsin.Job Description & Requirements.
Travel Physical Therapist (PT).Facility in Fond ...Show more
As one of the fastest-growing and most exciting brands in the industry, Crash Champions is the largest founder-led multi-shop operator (MSO) of high-quality collision repair service in the U.The co...Show more
Job Description & Requirements.StartDate : ASAP Pay Rate : $550000.A well-established physician-led, physician-driven organization in Wisconsin is seeking a dermatologist to join their practice.There...Show more
Genie Healthcare is seeking a travel Physical Therapist for a travel job in Fond Du Lac, Wisconsin.Job Description & Requirements Specialty : Physical Therapist Discipline : Therapy Start Date : 12 / 15...Show more
Details of the PT opening in Fond du Lac, WI : .Anticipated Start Date : 12 / 15 / 2025.Anticipated Pay Range : $1782 - $2058.
Work Setting : Outpatient Clinic.Anticipated Duration of Assignment : 13 Weeks.An...Show more
Fusion Medical Staffing is seeking an experienced CT Tech for an exciting Travel Allied job in West Bend, WI.Shift : Inquire Start Date : 12 / 15 / 2025 Duration : 12 weeks Pay : $2259 / Week.Facility in W...Show more
Premier Medical Staffing Services is seeking a travel Rehabilitation Therapist for a travel job in Fond Du Lac, Wisconsin.
Job Description & Requirements.Premier Medical Staffing Job ID #593174....Show more
Join Our Team at Walgreens as a Pharmacist!.Why Walgreens - For You, For Your Family, For Your Future.At Walgreens, pharmacists are medication experts and trusted healthcare providers reshaping the...Show more
ATI Physical Therapy Central_WI_Fond du Lac - W Johnson St.StaffDNA has several positions for Physical Therapist, Other at a healthcare facility in Fond Du Lac, WI.
Job Duties : Administers high qual...Show more
At PT Plus, we're more than a therapy clinic - we're a community of people dedicated to Touching Lives.Guided by our values of Local (committed to our communities), Service (for each other and our ...Show more
Skyline Med Staff Allied is seeking a travel Physical Therapist for a travel job in Fond Du Lac, Wisconsin.Job Description & Requirements Specialty : Physical Therapist Discipline : Therapy Start Dat...Show more
Synergy Medical Staffing is seeking a travel Physical Therapist for a travel job in Fond Du Lac, Wisconsin.Job Description & Requirements.
Location : Fond Du Lac, Wisconsin.Shift : 5x8 Days, 08 : 00 : 00-...Show more
AMN Healthcare Allied is seeking a travel Outpatient Physical Therapist for a travel job in FOND DU LAC, Wisconsin.Job Description & Requirements.
Job Description & Requirements.Physical The...Show more
Centra Healthcare Allied is seeking a travel Physical Therapist for a travel job in Fond du Lac, Wisconsin.Job Description & Requirements.
Centra Healthcare Solutions is seeking an experienced.P...Show more
Join one of the nation's largest, most respected health systems and experience what it means to live well.Advocate Health is seeking a Dermatologist to join our physician-led medical group and ...Show more Enhance Rehabilitation is currently seeking qualified Physical Therapists candidates to join our dynamic team.As an Enhance Rehabilitation Physical Therapist, you will be a part of growing team pro...Show more 
Premier Medical Staffing Services, LLC is seeking an experienced CT Tech for an exciting Travel Allied job in West Bend, WI.
Shift : 5x8 hr flex Start Date : 12 / 15 / 2025 Duration : 13 weeks Pay : $2340 / ...Show more
Full Time Physical Therapist (PT) - FDL
Enhance Rehabilitation • Fond du Lac, WI, United States
Full-time
Last updated: 30+ days ago • Promoted
Travel Physical Therapist
Fusion Medical Staffing-Therapy • Fond du Lac, WI, US
Full-time
Last updated: 30+ days ago • Promoted
Collision Estimator
Crash Champions • SLINGER, Wisconsin, US
Full-time
Last updated: 15 days ago • Promoted
Dermatology
AMN Healthcare • Fond Du Lac, US
Full-time
Last updated: 30+ days ago • Promoted
Travel Physical Therapist - Weekly Compensation of $2,290
Genie Healthcare • Fond du Lac, WI, United States
Full-time
Last updated: 1 hour ago • Promoted • New!
PT
National Staffing Solutions • Fond du Lac, WI, US
Full-time
Last updated: 1 day ago • Promoted
Travel CT Tech - $2259 / Week
Fusion Medical Staffing • West Bend, WI, US
Full-time
Last updated: 9 days ago • Promoted
Travel Rehabilitation Physical Therapist
Premier Medical Staffing Services • Fond du Lac, WI, US
Permanent
Last updated: 30+ days ago • Promoted
Pharmacist - Newly Increased Salary Range
Walgreens • West Bend, WI, United States
Full-time
Last updated: 4 days ago • Promoted
Physical Therapist - Other
ATI Physical Therapy Central_WI_Fond du Lac - W Johnson St • Fond du Lac, WI, United States
Full-time
Last updated: 4 days ago • Promoted
Physical Therapist
PT Plus • West Bend, WI, United States
Full-time
Last updated: 30+ days ago • Promoted
Travel Physical Therapist - $1,986 per week
Skyline Med Staff Allied • Fond du Lac, WI, United States
Full-time
Last updated: 4 days ago • Promoted
Travel Physical Therapist - $2,276 per week
Synergy Medical Staffing • Fond Du Lac, WI, United States
Permanent
Last updated: 19 days ago • Promoted
Travel Outpatient Physical Therapist
AMN Healthcare Allied • Fond du Lac, WI, US
Full-time
Last updated: 30+ days ago • Promoted
Travel Physical Therapist
Centra Healthcare Allied • Fond du Lac, WI, US
Full-time
Last updated: 30+ days ago • Promoted
Flourishing North Wisconsin Dermatology Practice - Turnkey - Outpatient Only
Advocate Health • Fond du Lac, US
Full-time
Last updated: 30+ days ago • Promoted
PRN PT - FDL
Enhance Rehabilitation • Fond du Lac, WI, United States
Full-time
Last updated: 4 days ago • Promoted
Travel CT Tech - $2340 / Week
Premier Medical Staffing Services, LLC • West Bend, WI, US
Full-time
Last updated: 9 days ago • Promoted