Senior Associate Scientist, Vaccine Downstream Bioprocess Development

The Senior Associate Scientist in Downstream Bioprocess Development plays an essential role in the Zoetis biopharmaceutical and vaccine strategies for veterinary medicine. The successful applicant will work as a junior team member in the development of purification processes in support of global product development and GMP (Good Manufacturing Practice) manufacture of veterinary biologics and recombinant proteins. The successful candidate is expected to work hands-on at the bench with appropriate direction while providing technical guidance to project teams within the discipline of biological manufacturing sciences. The Senior Associate Scientist is expected to work on cross-functional project teams in partnership with colleagues in early research, bacteriology, virology, formulation development, regulatory, and bioanalytical sciences. To be successful, they will have basic knowledge of chromatographic and filtration processes for processing traditional biologics antigens and purifying proteins from both mammalian and prokaryotic expression systems. They will serve as a technical resource within the line and will have a working knowledge of related bioprocessing unit operations such as cell culture, fermentation, formulation, and analytical characterization as it pertains to their workstream. The position is based in Kalamazoo (Michigan, USA) with frequent interactions with colleagues and external partners located around the globe.

Responsibilities :

• Assist in the development and optimization of robust, economical processes for biologics antigen production and for purification processes for recombinant proteins.
• Collaborate with pilot and manufacturing colleagues to successfully transfer developed processes to a commercial environment.
• Perform process characterization studies on process steps (including DOE approaches) to identify and define proven design and operational spaces with each process
• Serve as a technical resource for chromatography and filtration (cross-flow and dead-end) methods related to both therapeutic proteins and vaccines antigen targets.
• Perform antigen purification and / or viral and bacterial concentration to support mono- and multivalent vaccine development.
• Author protocols, study reports, and technology transfer documents that will support technology transfer within the company or to contract manufacturers and well as to support regulatory filings for new product registrations.
• Represent DSP and Process Development on interdisciplinary project teams.
• Contribute at the technical level to the direction of the team and guide decision making in the context of DSP or process development as a whole.
• Maintain electronic laboratory notebooks and records in accord with scientific protocol and applicable Standard Operating Procedures.

Basic Qualifications :

Preferred Qualifications :

Full time

Regular

Colleague

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About Zoetis

At Zoetis , our purpose is to nurture the world and humankind by advancing care for animals. As a Fortune 500 company and the world leader in animal health, we discover, develop, manufacture and commercialize vaccines, medicines, diagnostics and other technologies for companion animals and livestock. We know our people drive our success. Our award-winning culture, built around our Core Beliefs, focuses on our colleagues' careers, connection and support. We offer competitive healthcare and retirement savings benefits, along with an array of benefits, policies and programs to support employee well-being in every sense, from health and financial wellness to family and lifestyle resources.

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