Global Translational Medicine Lead

Do you want to be part of an inclusive team that works to develop innovative therapies for patients? Every day, we are driven to develop and deliver innovative and effective new medicines to patients and physicians.  If you want to be part of this exciting work, you belong at Astellas!

Astellas Pharma Inc. is a pharmaceutical company conducting business in more than 70 countries around the world. We are committed to turning innovative science into medical solutions that bring value and hope to patients and their families. Keeping our focus on addressing unmet medical needs and conducting our business with ethics and integrity enables us to improve the health of people throughout the world. For more information on Astellas, please visit our website at www.astellas.com .

This position is based in Northbrook, Illinois. Remote work from certain states may be permitted in accordance with Astellas’ Responsible Flexibility Guidelines. Candidates interested in remote work are encouraged to apply.

Purpose and Scope :

Lead the development and execution of Translational Medicine strategy to advance Astellas’s Ophthalmology projects. Candidates should have deep expertise in ophthalmology, vision science, and retinal diseases and record of accomplishment in developing and executing translational strategy from late discovery through clinical development. Ability to represent the TM function and work effectively on cross-functional teams is essential to the success of this position.

Responsibilities and Accountabilities :

• Develops and executes integrated translational science and biomarker development plans and defines patient selection strategies for clinical studies
• Develops and validate biomarkers, imaging readouts, and fluid-based assays relevant to ocular diseases
• Contributes to overall development strategy and trial design, incorporating biomarker endpoints
• Leads Translational Medicine activities and collaborates cross-functionally on asset development teams
• Works with clinical team for implementation of biomarker sample collection and bioanalysis
• Drives clinical biomarker data analysis and interpretation
• Contributes to clinical documents : protocols, IBs, study reports, statistical analysis plans, publications, CSR and biomarker sections of regulatory submissions
• Leads reverse translation, so that clinical results can be used to inform development strategy
• Establishes and leads Translational Medicine focused external collaborations
• Thinks strategically and drives innovation. Evaluates and incorporates emerging technologies and approaches in cell and gene therapy development