Scientist

ABOUT STRM.BIO STRM.BIO (pronounced “storm bio”) is a VC-backed biotech startup building a new kind of gene therapy delivery platform based on naturally occurring extracellular vesicles (EVs).

We're leveraging the unique biology of EVs to unlock targeted, scalable, and low-immunogenicity genetic medicines that target the bone marrow.

We’re a small, fast-moving team based at The Engine in Cambridge, MA.

We believe in simplicity, integrity, and keeping people at the center of everything we do.

We’re here to do great science and build a company we’re proud of.

THE OPPORTUNITY We’re looking for Scientists to help lead and grow our research engine.

You’ll work shoulder-to-shoulder with the VP of R&D, Director of Research, and a team of fellow Scientists to drive key programs forward and manage external collaborations.

This is a hands-on, highly cross-functional role ideal for someone who’s ready to dive in and execute in equal measure.

This is a full-time, on-site role.

WHAT YOU’LL DO (Key Responsibilities)  Support the Director of Research and R&D team in managing, coordinating, and supporting the research efforts across multiple collaborative research programs   Contribute to, and lead as required, R&D efforts to meet project milestones, maintaining the standards of scientific rigor and adhering to ethical standards   Maintain standards consistent with company culture and values   Work closely with team members (internal and external) to maintain project development, implementation and troubleshooting of experiments, and ensure deliverables for both internal research projects and external scientific partnerships   Generate, analyze, interpret, and share experimental results and ensure that all protocols, reagents, data, and analyses are documented following data integrity principles and prepared and made available in a timely manner   Attend and present at team meetings to share results, and plan projects and experiments, with a keen eye for achieving company milestones   Maintain comprehensive and up-to-date knowledge of extracellular vesicle biology, extracellular vesicles as therapeutics, and novel genetic engineering approaches   Perform other duties as assigned, including all those associated with facilitating the smooth operation of a wet lab environment WHAT YOU BRING (Required Qualifications) Ph.D. in molecular biology, immunology, bioengineering, or related field; strong background in genetic engineering / gene therapy (primary cells / hematopoietic lineages a plus) Experience in in vitro, ex vivo, and in vivo studies assessing gene delivery, editing, and expression Hands-on with T-cell–based assays / therapies (cytotoxicity, expansion, CAR-T); autoimmune models a plus Solid working knowledge of genome editing tools (CRISPR, TALEN, ZFNs) and therapeutic editing in preclinical models Strong bench skills in molecular / cell biology (qPCR, RT-PCR, Western, microscopy, multiplex flow cytometry) Experience designing / handling DNA & mRNA molecules; exposure to construct design and NGS workflows preferred Experience with non-viral delivery systems (viral vectors, LNPs, EVs) and associated analytics In vivo experience including vivarium work and animal model handling Familiarity with electronic lab notebooks (ELNs) preferred Experience collaborating with CROs / external partners; CMC familiarity a plus Excellent communicator, highly organized, detail-oriented, collaborative Proficient in Microsoft Office (Excel, PowerPoint) for data analysis / presentation Bonus :

• experience with startup ops, grant writing, or early product development KEY POSITION DETAILS 100% on-site in Cambridge, MA Full time with competitive compensation The salary range for this position is $110,000 to $135,000 USD annually.
• This salary range is an estimate, and the actual salary may vary based on various factors, including, without limitation, individual education, experience, tenure, skills, and abilities, as well as internal equity and alignment with market data, including potential adjustments for geographic location.   Powered by JazzHR