Research Scientist, Cell Biology – T Cell Biology

Our Client, a Biopharmaceutical company, is looking for a Research Scientist, Cell Biology – T Cell Biology for their Walnut Park, CA location.

Responsibilities:

• Execution of cell-based functional and biochemical assays to select candidate molecules for clinical development or support combination strategies to enhance T cell product potency and safety
• Experimental design aimed to address basic tumor immunology aspects related to the immunosuppressive tumor microenvironment
• Genetic/biochemical manipulation of T cells and evaluation of impact on T cell function
• Analyze, organize and communicate results at different research and cross-functional meetings
• Plan and effectively execute experiments based on strategy, project timelines and goals
• Analyze and present scientific results to the project team in addition to cross-functional and cross-site audiences
• Document experimental results to enable subsequent clinical studies and patent applications
• May serve as a core team member or leader on a project team
• Work effectively with other functions (including Process Development, Translational Medicine, Clinical Development) to ensure alignment cross-functionally
• Coordinate tasks across multiple projects, demonstrating prioritization and planning
• May mentor junior team members and supervise the work of a research team including, but not limited to, organizing and prioritizing laboratory work and review of generated experimental results

Requirements:

• Advanced scientific degree ( MD, PharmD, PhD) OR Master’s Degree and + years of scientific experience
• Experience designing and developing primary immune cell assays using key immune cell populations
• Hands-on expertise in T-cell functional characterization assays including in vitro cxytotoxicity, proliferation, cytokine/chemokine measurements, cell signaling, activation, differentiation and exhaustion
• Proficient in cell culture aseptic technique
• Proficient in multi-parameter flow cytometry (panel design, sample acquisition, data processing) and data analysis (FACSDiva, FlowJo, GraphPad Prism, Excel)
• Experience with MSD/ELISA and/or Luminex
• degree in biology-related field (immunology, cellular and/or tumor biology or a closely related field)
• A strong background in cancer immunotherapy and human immunology, experience working with engineered T cells strongly preferred
• Demonstrated independence in experimental design, data analysis, interpretation, and presentation
• Maintain a high degree of accuracy and attention to detail
• Drive to learn and make a meaningful impact
• Comfortable in a fast-paced company environment with minimal direction and able to adjust workload based upon changing priorities
• Strong collaboration, excellent interpersonal and communication skills
• Experience using both written and verbal communication, including presentations, to communicate results to a diverse cross-functional audience
• Strong organizational and record keeping skills
• Self-motivated, strong sense of responsibility, and willing to accept temporary responsibilities outside of initial job description

Why Should You Apply?

• Excellent growth and advancement opportunities