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Director / Senior Director, Drug Product Development

Director / Senior Director, Drug Product Development

Rapport TherapeuticsBoston, MA, United States
1 day ago
Job type
  • Full-time
Job description

Director / Senior Director, Drug Product Development

Join to apply for the Director / Senior Director, Drug Product Development role at Rapport Therapeutics .

When our people share why they joined Rapport and love it here, it comes down to three things : the science, the mission, and the team. At Rapport, we’re driven by a passion for developing precision neuromedicines with the potential for fewer side effects, enabling patients and their families to enjoy healthier, more fulfilling lives. And we’re doing this with extraordinary science and awesome people (affectionately called Rapptors).

Our innovative scientific platform is centered on Receptor Associate Proteins (RAPs). RAPs are a component of neuronal receptor complexes, which play a crucial role in regulating receptor assembly and function. This precision approach has the potential to revolutionize the development of small molecule therapies. We are excited about the potential of our lead program, RAP-219. Our first indication targets focal epilepsy with additional clinical trials for neuropathic pain and bipolar disorder.

The strength of Rapport comes from our Rapptors – who are united by our mission to improve patients lives. We bring the heart and hustle to advance our science forward, always staying true to our core values. We hope you’re as excited about this opportunity as we are!

Your Impact

In this role, you will serve as the technical and strategic leader for drug product development. You will drive formulation strategy, scale‑up, technology transfer, and GMP manufacturing across a global CDMO network. This role ensures we deliver robust, commercially viable product while maintaining speed, scientific rigor, and compliance.

Your Day‑to‑Day

Strategic Execution & Oversight

  • Lead the drug product strategy and manage manufacturing activities across all development phases.
  • Ensure alignment of CMC plans with program scope, timelines, and budget.

Technical Leadership

  • Guide process development for solid oral dosage and long‑acting injectable formulations.
  • Oversee technology transfers and GMP manufacturing with CDMOs.
  • Support scale‑up, process characterization, validation, and commercial readiness.
  • External Collaboration

  • Build and maintain strong relationships with domestic and international CDMOs.
  • Provide technical direction and budget oversight to external partners.
  • Operational Excellence

  • Coordinate with clinical operations and supply chain to ensure uninterrupted drug supply.
  • Ensure cGMP compliance, including batch documentation, deviation management, and audit support.
  • Regulatory Support

  • Author and review CMC sections of regulatory submissions (INDs, IMPDs, NDAs, briefing packages).
  • Contribute to regulatory strategy and documentation across the product lifecycle.
  • Cross‑Functional Leadership

  • Provide scientific and strategic input to project teams.
  • Drive intellectual property development and support cross‑functional initiatives.
  • Must‑Haves

  • MS. (12+ years) or Ph.D. (8+ years) in Pharmaceutical Sciences, Chemistry, Chemical Engineering, or related field preferred with a strong track record in formulation, manufacturing, and regulatory submissions.
  • Biotech experience strongly preferred.
  • Expertise in solid oral dosage forms and preference given to candidates with experience with long‑acting injectable formulations.
  • Proven experience in phase‑appropriate GMP execution.
  • Demonstrated success in managing CDMOs and leading technology transfer.
  • Familiarity with QbD principles, statistical tools, and design of experiments (DOE).
  • Strong leadership and communication skills with the ability to drive cross‑functional collaboration and deliver results.
  • What Makes Rapport Special

  • Every role has meaning. We’re determined to discover a better way for patients, and you’ll feel the passion from the start.
  • We are driven to innovate. Exciting science that pushes boundaries and opens new possibilities.
  • Your perspective matters. Stick your neck out, share your ideas – we work as a team.
  • We have FUN. We hire smart, dedicated, down‑to‑earth people that you’ll enjoy spending time with.
  • Leadership that CARES – about you, your growth + development.
  • We’re bicoastal. Whether you’re in the lab full‑time in San Diego or taking advantage of a more hybrid work schedule in Boston – we make the most of our time together.
  • Competitive benefits. Including unlimited PTO, a lifestyle spending account, commuting reimbursement, and much more!
  • You get to be YOU! Show up as you are and make every day count.
  • Your Compensation

    We get it. Compensation is an important part of your offer. You shouldn’t be surprised at the end of the recruiting process, and you should know that your offer is fair and equitable. How do we do this? We tell you about our hiring range now – we expect the hiring range for this role to be $230,000 to $250,000 for Director level or $260,000 to $290,000 for Senior Director level. Our actual offer will reflect a lot of factors including your relevant skills, experience, location, salary market data, and internal equity. In addition to a competitive salary, we also offer a pretty great benefits package.

    Hybrid Work Environment

    We prioritize in person connection with our fellow Rapptors! Our team members come together onsite at our Boston office on Tuesday and Wednesday. In January 2026, this will shift to three days a week to create more opportunities for innovation, collaboration, and connection.

    Rapport Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.

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