Postdoc Scientist- HIV / AIDS research and treatment at UCSF

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Postdoc Scientist- HIV / AIDS research and treatment at UCSF

Postdoc Scientist- HIV / AIDS research and treatment at UCSF

Location : United States

Job Posted Date : February 18, 2025

Population : The Yukl laboratory performs basic and translational research focused on understanding the barriers to curing HIV, with an emphasis on investigating the mechanisms that allow HIV-infected cells to persist in the blood and tissues. Research areas include :

• Mechanisms that govern latent HIV infection / reactivation and the regulation of HIV transcription;
• Cellular factors involved in HIV latency and HIV expression;
• Differences between blood and tissues in the types of HIV reservoirs, their mechanisms of persistence, and their responses to therapies aimed at curing HIV;
• Contribution of HIV-expressing cells to immune activation / inflammation and viral rebound after interruption of antiretroviral therapy;
• Development and testing of new therapies to disrupt latent HIV infection (latency reversing agents, latency promoting agents) or induce selective killing of HIV-infected cells.
• Development of new assays to quantify HIV reservoirs and investigate mechanisms of HIV latency / persistence.

In addition, we have projects aimed at understanding the transcriptional regulation and pathogenesis of SARS-CoV-2, the etiologic agent of COVID-19. These projects involve the implementation and development of laboratory assays to apply to samples from infected and uninfected individuals, as well as cell lines and primary cells infected in vitro. We also pursue collaborative mechanistic studies with other investigators throughout the San Francisco Bay Area, the United States, and many other countries.

Our lab’s mission is to train the next generation of HIV cure researchers under the mentorship of Dr. Yukl, other lab members, and collaborating investigators. Training will be provided to enable the candidate to engage in multiple different laboratory projects. In addition to training in laboratory techniques, candidates will be provided with opportunities to present their research at national and international meetings, write manuscripts, and apply for independent grant funding.

Job responsibilities include but are not limited to :

Job Requirements :

Required Qualifications :

A two-year commitment is expected. Depending on performance and workload, opportunities for independent research, mentorship of other trainees, and scientific writing will be available.

As a University employee, you will be required to comply with all applicable University policies and / or collective bargaining agreements, as may be amended from time to time. Federal, state, or local government directives may impose additional requirements.

UC San Francisco seeks candidates whose experience, teaching, research, or community service has prepared them to contribute to our commitment to diversity and excellence. The University of California is an Equal Opportunity / Affirmative Action Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, age, or protected veteran status.

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