Talent.com
Oncologist - Clinical Research Leadership
Oncologist - Clinical Research LeadershipPlexus Partners • San Francisco, CA, US
Oncologist - Clinical Research Leadership

Oncologist - Clinical Research Leadership

Plexus Partners • San Francisco, CA, US
5 days ago
Job type
  • Full-time
Job description

Oncologist / Principal Investigator - Clinical Research leadership

Location : Los Angeles, CA

Employment Type : Full-Time, On-Site

Overview

We are representing an exceptional research-focused oncology organization seeking a Principal Investigator (PI) to oversee a highly experienced clinical team and drive breakthrough studies with biotech sponsors.

This is a full-time, research-only role , offering the opportunity to guide cutting-edge oncology trials in a fast-growing, data-driven clinical environment.

The position is ideal for an oncologist who wants to transition from purely clinical practice into a leadership role at the intersection of science, medicine, and industry , helping advance next-generation cancer therapies.

Key Responsibilities

  • Serve as the Principal Investigator for oncology trials across multiple modalities and sponsors.
  • Provide medical oversight, ensure patient safety, and maintain protocol compliance and data integrity.
  • Supervise and mentor sub-investigators, nurse practitioners, and clinical operations staff.
  • Collaborate closely with sponsors, CROs, and internal study teams to drive enrollment and site performance.
  • Support scientific and operational strategy, SOP refinement, and future site development.
  • Participate in investigator meetings, safety reviews, and regulatory inspections.

Ideal Candidate

  • MD or DO with board certification or eligibility in Hematology / Oncology (or related discipline).
  • Licensed or license-eligible to practice medicine in California.
  • 1–5+ years post-fellowship experience (early-career attendings encouraged to apply).
  • Demonstrated clinical excellence and the ability to manage oncology patients in a research setting.
  • Prior Sub-I or PI experience preferred but not required — full GCP training and mentorship provided.
  • Strong communication skills, collaborative mindset, and enthusiasm for research and innovation.
  • Must be committed to a full-time, on-site position.
  • Why This Opportunity

  • Exceptional Organization — culture of scientific rigor, integrity, and collaboration.
  • Exposure to Cutting-Edge Oncology Programs — work on next-generation therapeutic approaches.
  • Leadership Trajectory — opportunity to expand into multi-site or network-level leadership.
  • Competitive Compensation — highly attractive package with relocation and performance incentives.
  • This search is being managed exclusively by Plexus Partners.

    Interested candidates can submit a CV or express interest in confidence to :

    elliot@plexus-partners.com

    Create a job alert for this search

    Oncologist - Clinical Research Leadership • San Francisco, CA, US

    Related jobs
    Senior Clinical Research Coordinator

    Senior Clinical Research Coordinator

    University of California - San Francisco Campus and Health • San Francisco, CA, United States
    Part-time
    Senior Clinical Research Coordinator.Senior Clinical Research Coordinators independently coordinate and are accountable for the overall administration of one or more clinical studies, typically req...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Research Coordinator - Thoracic Oncology and Sarcoma Program

    Clinical Research Coordinator - Thoracic Oncology and Sarcoma Program

    University of California - San Francisco Campus and Health • San Francisco, CA, United States
    Full-time
    Clinical Research Coordinator - Thoracic Oncology and Sarcoma Program.The Clinical Research Coordinator will perform independently or with general direction at the fully operational journey level o...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Research Coordinator

    Clinical Research Coordinator

    University of California - San Francisco Campus and Health • San Francisco, CA, United States
    Full-time
    The JJBH Clinical Research Coordinator position is with Dr.Marina Tolou-Shams' Juvenile inJustice Behavioral Health (JJBH) research team in the Department of Psychiatry at the University of Califor...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Research Supervisor

    Clinical Research Supervisor

    University of California - San Francisco Campus and Health • San Francisco, CA, United States
    Full-time
    Helen Diller Family Comprehensive Cancer Center (HDFCCC).The research program is a fast-paced environment and the successful candidate will be an independent, detail-oriented individual with drive ...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Development Medical Director (Oncology)

    Clinical Development Medical Director (Oncology)

    Exelixis • Alameda, CA, United States
    Full-time
    In collaboration with the Exelixis clinical teams, the primary role is to lead and execute early / late stage oncology clinical trials for oncology products in development. Participates in the design / ...Show more
    Last updated: 30+ days ago • Promoted
    Oncologist BC / BE

    Oncologist BC / BE

    HealthEcareers - Client • Sunnyvale, CA, USA
    Full-time
    Palo Alto Foundation Medical group is seeking a full-time, board-certified oncology physician for our thriving Cancer Genetics and Prevention Program. Work at a state-of-the-art cancer center .Manag...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Research Coordinator - Melanoma and Cutaneous Oncology Program

    Clinical Research Coordinator - Melanoma and Cutaneous Oncology Program

    University of California - San Francisco • San Francisco, CA, United States
    Full-time
    Clinical Research Coordinator - Melanoma and Cutaneous Oncology Program.HDF Comprehensive Cancer Center.The Cutaneous Oncology clinical research team supports a diverse portfolio of studies for mel...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Research Coordinator - Oral, Head, and Neck Oncology

    Clinical Research Coordinator - Oral, Head, and Neck Oncology

    University of California - San Francisco Campus and Health • San Francisco, CA, United States
    Full-time
    Clinical Research Coordinator - Oral, Head, and Neck Oncology.HDF Comprehensive Cancer Center.The Oral, Head, and Neck Oncology clinical research team is unique in its diverse study portfolio, whic...Show more
    Last updated: 30+ days ago • Promoted
    Oncology Study Manager

    Oncology Study Manager

    VirtualVocations • Santa Clara, California, United States
    Full-time
    A company is looking for a Study Manager - Oncology - Home Based (US / Canada).Key Responsibilities Assist the Study Manager Lead and team with operational conduct of clinical studies Support a si...Show more
    Last updated: 9 hours ago • Promoted • New!
    Clinical Research Associate II (Contractor)

    Clinical Research Associate II (Contractor)

    Dynavax Technologies • Emeryville, CA, United States
    Temporary
    This position can be 100% remote, but must be located in the United States.Dynavax is a commercial-stage biopharmaceutical company developing and commercializing novel vaccines to help protect the ...Show more
    Last updated: 20 days ago • Promoted
    Clinical Research Coordinator - Melanoma and Cutaneous Oncology Program

    Clinical Research Coordinator - Melanoma and Cutaneous Oncology Program

    University of California - San Francisco Campus and Health • San Francisco, CA, United States
    Full-time
    Clinical Research Coordinator - Melanoma and Cutaneous Oncology Program.HDF Comprehensive Cancer Center.The Cutaneous Oncology clinical research team supports a diverse portfolio of studies for mel...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Research Associate

    Clinical Research Associate

    Calyxo, Inc. • Pleasanton, CA, United States
    Full-time
    The company was founded in 2016 to address the profound need for improved kidney stone treatment.Kidney stone disease is a common, painful condition that consumes vast amounts of healthcare resourc...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Research Supervisor - Cutaneous Oncology Program

    Clinical Research Supervisor - Cutaneous Oncology Program

    University of California - San Francisco Campus and Health • San Francisco, California, United States
    Full-time
    Clinical Research Supervisor - Cutaneous Oncology Program.Helen Diller Family Comprehensive Cancer Center (HDFCCC).The Helen Diller Family Comprehensive Cancer Center (HDFCCC) is seeking a.Clinical...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Research Coordinator

    Clinical Research Coordinator

    University of California - San Francisco • San Francisco, CA, United States
    Full-time
    The Clinical Research Coordinator will perform independently execute, manage, and coordinate research protocols, as directed by the Clinical Research Supervisor and / or Principal Investigator (PI); ...Show more
    Last updated: 30+ days ago • Promoted
    Clinical Trial Associate II (Contractor)

    Clinical Trial Associate II (Contractor)

    Dynavax Technologies • Emeryville, CA, United States
    Full-time
    This position can be 100% remote, but must be located in the United States.Dynavax is a commercial-stage biopharmaceutical company developing and commercializing novel vaccines to help protect the ...Show more
    Last updated: 20 days ago • Promoted
    Cleveland, OH based Clinical Specialist

    Cleveland, OH based Clinical Specialist

    Calyxo, Inc. • Pleasanton, CA, United States
    Full-time
    The company was founded in 2016 to address the profound need for improved kidney stone treatment.Kidney stone disease is a common, painful condition that consumes vast amounts of healthcare resourc...Show more
    Last updated: 9 days ago • Promoted
    Clinical Research Coordinator 2

    Clinical Research Coordinator 2

    Stanford University • Redwood City, California, United States
    Full-time
    The Department of Orthopaedic Surgery is seeking a Clinical Research Coordinator 2 (CRC2) to conduct clinical research and manage the clinical research studies with Trauma Services which specialize...Show more
    Last updated: 12 days ago • Promoted
    Clinical Research Supervisor - Cutaneous Oncology Program

    Clinical Research Supervisor - Cutaneous Oncology Program

    University of California - San Francisco • San Francisco, California, United States
    Full-time
    Clinical Research Supervisor - Cutaneous Oncology Program.Helen Diller Family Comprehensive Cancer Center (HDFCCC).The Helen Diller Family Comprehensive Cancer Center (HDFCCC) is seeking a.Clinical...Show more
    Last updated: 30+ days ago • Promoted