Scientist Protein Biophysical Analysis (Spring House)

Our large pharmaceutical client is seeking a Scientist for Protein Biophysical Analysis to join the growing Binding Group. This team focuses on developing and applying preclinical assays to support the discovery of therapeutic candidates. The ideal candidate will have strong expertise in biophysical and biochemical characterization, with a focus on affinity analysis methods.

Key Responsibilities

• Conduct kinetics and affinity analysis of antigens and antibodies using SPR (Biacore, Proteon), BLI (Octet), and KinExA.
• Perform HPLC analyses to assess hydrophobicity, size, and purity of proteins.
• Characterize molecules using mass spectrometry (MS) .
• Analyze data, document results, and maintain records in ELNs and LIMS .
• Maintain lab instruments, including cleaning spray sources, weekly calibration, and preparing calibration solutions.
• Support assay development, validation, and bioanalysis efforts as needed.
• Assist in drafting and executing peer-reviewed posters, manuscripts, technical reports, and patent filings .

Required Skills & Experience