Job Description
Opportunity : Principal Investigator (General Medicine)
Metric Bio is partnering with a high-performing and rapidly expanding clinical site network based in Massachusetts, in the search for an accomplished Principal Investigator specialising in General Medicine . This is a unique opportunity to lead meaningful clinical research, drive innovation, and directly impact patient outcomes within a cutting-edge US-based organisation.
The Role :
As the Principal Investigator, you will provide expert medical leadership across multiple clinical trials, ensuring scientific integrity, regulatory compliance, and the highest standards of patient safety. You’ll be a key contributor in shaping research strategy, guiding clinical teams, and building strong collaborations with sponsors and stakeholders.
Key Responsibilities
- Serve as the lead Principal Investigator across general medicine clinical trials
- Oversee all aspects of study conduct, ensuring alignment with protocol, GCP, and FDA standards
- Conduct medical evaluations, determine eligibility, and monitor patient safety
- Provide expert input into feasibility assessments and study design
- Safeguard data quality and ethical integrity across trials
- Develop and maintain strong sponsor and regulator relationships
- Mentor and support Sub-Investigators and research teams
- Champion clinical excellence and continuous process improvement
Required Qualifications & Experience
MD / DO with active and unrestricted US medical license.Minimum 5 years’ post-licensure experience in general or internal medicineDirect involvement in 10 or more clinical trials (Phase II–IV preferred) as Principal Investigator or Sub-Investigator.Deep understanding of GCP, FDA regulations, ICH guidelines, and clinical governanceProven track record in clinical leadership and decision-makingExcellent communication, patient-centric approach, and collaborative mindsetWhat’s on Offer
Competitive compensation package + comprehensive benefitsOpportunity to lead high-impact trials across varied therapeutic areasInnovative, collaborative research environmentProfessional development & leadership supportMake a significant contribution to improving future patient careInterested in Applying?
If you are an experienced physician with a passion for research leadership and meet the clinical trial experience requirement, we would love to hear from you.
Contact Metric Bio : oli.oldham@metric-search.com