Scientist (Peptidomimetic Synthesis), R&D Chemistry We are currently seeking a lab‑centric peptide chemist to join the R&D Chemistry group. You will play a key role in Regeneron's peptidomimetic antibody‑conjugate drug discovery capabilities, enabling seamless combination with our existing expertise in biologics and novel genetic medicines. The candidate will drive the synthesis and discovery of peptidomimetic payloads and linker payloads for antibody conjugate drug therapeutics across diverse research areas. Responsibilities Actively participate and collaborate in the day‑to‑day activities of the R&D Chemistry Peptidomimetic group. Perform medicinal chemistry inspired and SAR‑driven synthesis of novel peptidomimetic drug modality payloads/linker payloads, using modern peptide synthesizers and characterization instrumentation. Troubleshoot and optimize peptide potency and stability using standard peptide‑based principles (e.g., Ala scans), non‑natural amino acid incorporation, α‑Me/N‑Me peptide backbone modifications, and other medicinal chemistry strategies guided by in vitro assays, plasma/serum stability, and met ID data. Participate in R&D Chemistry Peptidomimetic efforts on internal/external project teams, and demonstrate the ability to multi‑task and parallel process to add to our continuous pipeline of Regeneron peptidomimetic conjugates. Identify new strategies and technologies to improve existing Regeneron platforms for pursuing novel synthesis of peptidomimetic drug modality conjugates. Actively participate in departmental, cross‑functional, leadership, and external meetings to contribute expertise and to represent the vision of the R&D Chemistry Peptidomimetic group. Interact broadly and collaboratively with other Regeneron groups, forging relationships and active collaborations. Qualifications Bachelor’s degree required, Master’s degree preferred in peptide/peptidomimetic and/or synthetic organic chemistry (or related). Extensive hands‑on experience in the synthesis and reaction troubleshooting of peptidomimetics, and extensive experience running modern synthesis, isolation, and characterization equipment. Expertise in modern methods of peptidomimetic synthesis and analytical characterization, and a minimum of 5‑10 years of industry experience. A track record of success in the field of either peptidomimetics or small molecules is required. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief, sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship. Salary range: $93,900.00 – $153,300.00 annually. #J-18808-Ljbffr
Scientist, R&D Chemistry, Peptidomimetic Synthesis • Ossining, NY, United States
Description Prime Video is a first-stop entertainment destination offering customers a vast collection of premium programming in one app available across thousands of devices.Prime members can cus... Mostrar más
Eikon Therapeutics is a new biopharmaceutical company employing revolutionary technology at the intersection of chemistry, engineering, computation, and biology to discover novel treatments for lif... Mostrar más
The position is located in New York City.The research associate will work in conjunction with and support the senior research analyst in all aspects of developing and marketing equity research prod... Mostrar más
We are sharing a specialised part-time consulting opportunity for professionals experienced in chemistry, analytical chemistry, laboratory experimentation, chemical data analysis, scientific report... Mostrar más
Senior Therapeutic Area Specialist, Neuroscience - Zeposia - Jersey City, NJ.Those aren't words that are usually associated with a job.But working at Bristol Myers Squibb is anything but usual.Here... Mostrar más
Senior Group Director Scientist.Location: Gaithersburg, MD (may consider other locations including Cambridge, MA, New York, NY, South San Francisco, CA).The Senior Group Director Scientist is a sen... Mostrar más
R&D Manager/Principal Scientist - Polymer Formulation.Cresilon is a Brooklyn-based biotechnology company that develops, manufactures, and markets hemostatic medical devices utilizing the company's... Mostrar más
Specialised Part-Time Consulting Opportunity.We are sharing a specialised part-time consulting opportunity for professionals experienced in physical sciences, experimental research, quantitative da... Mostrar más
Biosecurity & Synthetic Biology Expert.Develop a comprehensive taxonomy for biological misuse scenarios, incorporating current and emergent threats.Design safe and realistic evaluation scenario... Mostrar más
Director of the Histology Core Facility.Cold Spring Harbor Laboratory is seeking an experienced and highly collaborative Ph.Director of the Histology Core Facility.The successful candidate will pro... Mostrar más
Blue Matter is a rapidly growing management consultancy focused primarily in the biopharmaceutical industry.We partner with our clients to help them achieve commercial success across the lifecycle ... Mostrar más
NYU Grossman School of Medicine is one of the nation's top-ranked medical schools.For 175 years, NYU Grossman School of Medicine has trained thousands of physicians and scientists who have helped t... Mostrar más
Vice President of Translational Sciences.Innovative biotech company specializing in cancer treatment & click chemistry technology.The Company is seeking a VP of Translational Sciences to play a piv... Mostrar más
PJT Partners is a global advisory-focused investment bank.Our team of senior professionals delivers a wide array of strategic advisory, shareholder advisory, restructuring and special situations an... Mostrar más
Vice President, Healthcare Group.Lazard is one of the world's preeminent financial advisory and asset management firms.Our people and culture make the difference.While global in presence and reach,... Mostrar más
PharmaLogic is the fastest-growing SPECT & PET radiopharmaceutical solutions provider and contract development and manufacturing organization (CDMO) with radiopharmacies across North America.We... Mostrar más
Research Associate, Semiconductors & Semiconductor Capital Equipment.Overview: This position sits within the Equity Research Department.The US Equity Research Department at Deutsche Bank is a top p... Mostrar más
Headquartered in San Francisco, our investors include.STEM Computational Scientific Software & Evaluation Design - Astrophysics & Cosmology.Design graduate-level computational problems usin... Mostrar más
Director, Translational Science (Neurology).At Eisai, satisfying unmet medical needs and increasing the benefits healthcare provides to patients, their families, and caregivers is Eisai's human hea... Mostrar más
We are sharing a specialised part-time consulting opportunity for professionals experienced in physical sciences, experimental research, quantitative data analysis, scientific reporting, technical ... Mostrar más
