Sr. Expert, Product Sciences - Cell Therapy Analytical Development

Job Description Summary

Internal Title : Senior Expert Science & Technology

Location : East Hanover, NJ, United States (On-Site)

This position will be located at East Hanover site and will not have the ability to be located remotely.

We are seeking a highly skilled and driven Senior Expert in Product Sciences to join our team in advancing transformative cell therapy products. Reporting to the Director of Product Sciences, this role focuses on driving product characterization efforts, incorporating immunological principles, and developing innovative scientific approaches to solve complex challenges in the cell therapy space. As a senior bench scientist, you will leverage your expertise in immunology, cell biology, and advanced analytical methods to generate actionable product insights and support the development of safe and efficacious cell therapy products that meet our target profiles. This role requires hands-on work in a fast-paced environment, applying scientific rigor and industry knowledge to enable data-driven decision-making.

Job Description

Key Responsibilities :

• Develop and refine advanced product characterization methods to assess quality attributes of cell therapy products, intermediates and starting material.
• Design and execute innovative assays to assess T cell function, lineage, cytokine production, proliferation, cytotoxicity, memory composition, differentiation, exhaustion, metabolic profiling, and omics profiling. Qualify appropriate assay parameters to ensure characterization assays are fit for purpose.
• Apply critical thinking skills to identify the right scientific questions aligned with product development goals. Independently design and execute experiments to address foundational and applied questions, leveraging immunological principles and cell therapy expertise.
• Ensure effective data collection, management, and analysis to drive data-driven decision-making processes. Support regulatory filing by providing high-quality data, technical reports, and scientific rationale.
• Collaborate with teams across Analytical Development, Process Development, Regulatory CMC, Biostatistics and Data Sciences to drive cell therapy programs forward.
• Share scientific knowledge and assay development expertise to inform decisions on attribute criticality, specification setting, and control strategies.
• Stay up to date on advances within immunology, cell therapy sciences, and analytical technologies.
• Work proactively (i.e. using statistical methodologies) to address challenges in manufacturing success and clinical outcomes through product and process understanding.

Requirements :

Desirable Requirements :

The salary for this position is expected to range between $114,100 and $211,900 per year.

The final salary offered is determined based on factors like, but not limited to, relevant skills and experience, and upon joining Novartis will be reviewed periodically. Novartis may change the published salary range based on company and market factors.

Your compensation will include a performance-based cash incentive and, depending on the level of the role, eligibility to be considered for annual equity awards.

US-based eligible employees will receive a comprehensive benefits package that includes health, life and disability benefits, a 401(k) with company contribution and match, and a variety of other benefits. In addition, employees are eligible for a generous time off package including vacation, personal days, holidays and other leaves.

EEO Statement :

The Novartis Group of Companies are Equal Opportunity Employers. We do not discriminate in recruitment, hiring, training, promotion or other employment practices for reasons of race, color, religion, sex, national origin, age, sexual orientation, gender identity or expression, marital or veteran status, disability, or any other legally protected status.

Accessibility and reasonable accommodations

The Novartis Group of Companies are committed to working with and providing reasonable accommodation to individuals with disabilities. If, because of a medical condition or disability, you need a reasonable accommodation for any part of the application process, or to perform the essential functions of a position, please send an e-mail to us.reasonableaccommodations@novartis.com or call +1(877)395-2339 and let us know the nature of your request and your contact information. Please include the job requisition number in your message.

Salary Range

$114,100.00 - $211,900.00

Skills Desired

Coaching Skills, Data Science, Environment, Experiments Design, Health And Safety (Ehs), Laboratory Equipment, Manufacturing Process, Materials Science, Process Simulation, Sop (Standard Operating Procedure), Technical Writing, Waterfall Model