Scientist- Talbot Laboratory, Departments of Surgery and Bone Marrow Transplantation and Cell Therapy

The Talbot laboratory embedded within the Department of Bone Marrow Transplantation and Cell Therapy at St. Jude Childrens Research Hospital is seeking to hire a dedicated and exceptional Scientist to lead studies in pediatric immune-oncology and solid tumor CAR T cell development. Our laboratory is part of a larger team of collaborative scientists within the Departments of Surgery and BMTCT with the ultimate goal of improving T-cell based immunotherapy targeting solid tumors and a focus on clinically translatable processes and results. The Talbot laboratory is specifically focused on understanding how transgenic wild type and mutated chemokine receptors can be exploited to drive homing of immune cells towards target pediatric tumors and confer enhanced biology as well as understanding underlying microenvironmental interactions.

Talbot Laboratory Departments of Surgery and Bone Marrow Transplantation and Cell Therapy

We are seeking a highly motivated individual with an interest in immunotherapy and basic immunology who seeks a work environment in which he / she has the opportunity to drive forward projects independently within the scope of the PIs overall research umbrella. Active questioning hypothesis generation independent experimental work and scientific curiosity are particularly encouraged.

The ideal candidate will have :

A PhD in immunology immunotherapy or a related discipline.

Extensive experience studying immune cell biology immunotherapy or related disciplines

Extensive experience with aseptic cell tissue culture flow cytometry molecular biology and in vivo work with survival surgery experience particularly appreciated

Experience working with immune competent tissues including tumor and tissue dissociation and immune cell subset recovery and analysis

Experience with generation of single cell datasets from dissociated tissues

Ability to independently design and execute experiments and interpret data inclusive of figure generation and statistical analysis

Ability to work in a multidisciplinary highly collaborative environment with excellent interpersonal skills

Excellent oral and written communication skills

Excellent multitasking abilities

Strong publication record

Track record of success training junior scientists and colleagues

Job responsibilities :

• Coordinates multiple aspects of research projects and carries out laboratory experiments utilizing various laboratory techniques and determines whether additional or other tools or methods are required
• Provides input regarding research protocols and experiments. Sets up protocols and assists in developing new laboratory techniques as required.
• Identifies experimental data pertinent to the analysis problem. Processes organizes and summarizes data reporting these experimental results as required. Monitors quality and integrity of recorded information and data. Maintains excellent laboratory and experimental records.
• May draft sections of research manuscripts and grant applications
• Provides basic lab operation support to include equipment maintenance and purchasing. Monitors inventory levels and orders lab supplies as needed. Performs calibration of instruments and equipment. Troubleshoots instrument performance and equipment issues.
• Instructs other staff in laboratory techniques and procedures.
• Maintains regular and predictable attendance
• Performs other related duties as assigned in order to meet the goals of the department and institution

Minimum Education and / or Training :

Minimum Experience :

Professional Growth Opportunities

We invite motivated scientists passionate about preclinical murine models and immuno-oncology to apply and join us in pushing the boundaries of immuno-oncology and immunotherapy in the fight against pediatric cancers.

Compensation

In recognition of certain U.S. state and municipal pay transparency laws St. Jude is including a reasonable estimate of the compensation range for this role. This is an estimate offered in good faith and a specific salary offer takes into account factors that are considered in making compensation decisions including but not limited to skill sets experience and training licensure and certifications and other business and organizational needs. It is not typical for an individual to be hired at or near the top of the salary range and compensation decisions are dependent on the facts and circumstances of each case. A reasonable estimate of the current salary range is $86320 - $154960 per year for the role of Scientist- Talbot Laboratory Departments of Surgery and Bone Marrow Transplantation and Cell Therapy.

Explore our exceptional benefits!

St. Jude is an Equal Opportunity Employer

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Key Skills

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Employment Type : Full-Time

Experience : years

Vacancy : 1

Yearly Salary Salary : 86320 - 154960