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Production Chemist
Production ChemistAstrix Inc • Torrance, CA, United States
Production Chemist

Production Chemist

Astrix Inc • Torrance, CA, United States
Hace más de 30 días
Tipo de contrato
  • Indefinido
Descripción del trabajo

Pharmaceutical Company in Los Angeles, CA is seeking a Production Chemist to join their Production team! This is a direct hire opportunity! Eagerly hiring!

Shift: Monday-Friday 8-5pm, with occasional shift to 2nd (2pm-10pm)
Must have: 1 year of HPLC

Responsibilities:

  • Perform purification process by chromatography, crystallization and other techniques, and in-process test method
  • Follow approved GMP manufacture directions such as Master Batch Records, Standard Operation Procedures, Standard Test Procedures and other procedures to manufacture GMP materials, perform in-process test, package the product including other related activities
  • Perform project-planning and initiate raw material order-request. Receive raw materials, coordinate with QA/QC and Material Management for material release and monitor raw material inventories
  • Install, test equipment, operate and maintain equipment for manufacturing and in-process testing. The equipment includes analytical HPLC and prep HPLC system, Lyophilizes, balances, reactors, HF cleavage equipment, diafiltration systems, water purification systems, oven, washing systems and others used in manufacture
  • Develop processes for purification of chemicals other than peptides
  • Follow and maintain GMP Documentation System. Investigate any process deviation and write process deviation report. Initiate document change request. Help quality control and assurance unit to maintain equipment calibration program
  • Routinely maintain/organize work areas (Hood, bench, floor, wall, etc.) and other designated areas at the manufacturing facility
  • Develop peptide-manufacturing processes including peptide/protein purification by chromatography, crystallization, and other techniques, and in process test methods
  • Assist QA/QC for monitoring raw material inventories
  • Write Standard Operation Procedures, Standard Test Procedures, Master Batch Records and other related GMP documents
  • Follow SOPs and approved directions to clean equipment used in GMP processes, maintain cleaning log for each equipment, assist in equipment calibration program, and dispose chemical waste generated in the manufacture
  • Monitor compliance of Maintenance and Cleaning procedures of equipment and instruments used in GMP processes by periodically reviewing and signing off on maintenance and cleaning log for each equipment
Requirements:
  • BS degree in Chemistry or related field
  • 1-5 years' work experience
  • Experience with HPLC and chromatography
  • May work with hazardous materials and chemicals
  • Excellent written and oral communication skills
  • Basic computer knowledge, including Microsoft Word, Excel and PowerPoint
  • Ability to effectively organize, multitask, and work in a fast-paced, deadline driven work environment
  • Ability to communicate in a proactive and solution-focused manner, including keeping management aware of potential issues.
  • Detail oriented with the ability to troubleshoot and resolve problems
  • Ability to work independently and manage one's time
  • Communicate effectively and ability to function well in a team environment
  • Flexibility of working hours based on business needs, may include some nights and occasional weekends
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Production Chemist • Torrance, CA, United States

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