Senior Research Associate, CryoEM

About Generate : Biomedicines

Generate : Biomedicines is a new kind of therapeutics company - existing at the intersection of machine learning, biological engineering, and medicine - pioneering Generative Biology™ to create breakthrough medicines where novel therapeutics are computationally generated, instead of being discovered. The Company has built a machine learning-powered biomedicines platform with the potential to generate new drugs across a wide range of biologic modalities. This platform represents a potentially fundamental shift in what is possible in the field of biotherapeutic development.

Location : Andover, MA (On-site, Full-Time)

Generate Biomedicines is seeking a Senior Research Associate to join our CryoEM Group in generating large-scale protein structural datasets. This role offers the opportunity to work at the intersection of protein biochemistry and cutting-edge structural biology, contributing to our mission of accelerating drug discovery through advanced imaging technologies.

How You Will Contribute

• Drive the advancement of experiments and technologies by performing protein purification, complexation, vitrification, and clipping, ensuring high-quality sample preparation for CryoEM.
• Operate CryoEM microscopes and execute automated data collection workflows with minimal guidance.
• Interpret and troubleshoot experimental data, contributing to planning and prioritization of concurrent CryoEM experiments.
• Apply and refine data analysis methods; determine reliability of results and communicate findings in presentations or team meetings.
• Collaborate with multidisciplinary teams to support high-throughput protein structure determination.
• Document experimental data and report findings in internal databases.
• Contribute to process optimization and implementation of new protocols.

Qualifications

Preferred Additional Skills

Experience

Additional Information

On-site position at our Andover, MA CryoEM lab.

Generate : Biomedicines is committed to equal employment opportunity regardless of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity or Veteran status.

Recruitment & Staffing Agencies : Generate : Biomedicines does not accept unsolicited resumes from any source other than candidates. The submission of unsolicited resumes by recruitment or staffing agencies to Generate : Biomedicines or its employees is strictly prohibited unless contacted directly by the Company's internal Talent Acquisition team. Any resume submitted by an agency in the absence of a signed agreement will automatically become the property of Generate : Biomedicines and the Company will not owe any referral or other fees with respect thereto.

Compensation

The base salary range provided reflects our current estimate of what we anticipate paying for this position. Your actual base salary will be based on several factors, including job-related skills, experience, internal equity, relevant education or training, and market dynamics. In addition, you will be eligible for an annual bonus, equity compensation, and a competitive benefits package.

$83,000-$108,000 USD

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