Principal Full Stack Engineer, AI Platform & Agents (US / Canada Hybrid / Remote)

Principal Full Stack Engineer, AI Platform & Agents

Build the GenAI platform that powers critical decisions in healthcare, legal, tax, and compliance industries. Your work will directly shape the future of these fields, enabling faster, safer, and more impactful decision-making at a global scale.

• Location : US / Canada, Hybrid or Remote
• Work Hours : Must have 9–11 AM CST overlap

Candidates within commuting distance of a Wolters Kluwer office will be considered for hybrid employment, with 2 days per week onsite.

Candidates not within commuting distance will be considered for remote employment .

About this role

Our team is building a central GenAI Platform to empower hundreds of product teams across the organization with scalable capabilities for rapid development, validation, and deployment of AI agents. We also drive the development of the most impactful AI agents, ensuring faster delivery and greater impact across multiple domains. With over 20 agents already launched and many more in progress, our work accelerates innovation and improves outcomes in critical industries.

You'll join a 100-engineer remote-first team within a larger organization that combines the stability of an established company with the agility of a startup. In this high-autonomy, high-impact role, you'll take problems from concept to production, mentor less experienced engineers, and lead by example. You'll design and ship full-stack systems, shape platform capabilities to empower hundreds of product teams, and directly contribute to the development of the most impactful AI agents.

Flagship Agent : UpToDate Expert AI

In Health, we’re launching  UpToDate Expert AI —a medical research and clinical reasoning agent that transforms the world’s most widely used point‑of‑care knowledge resource into a real‑time medical assistant. Millions of physicians will rely on it to accelerate differential diagnosis, refine treatment decisions, and reduce cognitive load—while maintaining rigorous safety, privacy, and guideline fidelity. Improvements you ship (latency, reliability, hallucination reduction) will translate directly into faster, higher-quality patient care at global scale.

Tech stack

You don’t need to know all of these on day one, but you should be ready to learn quickly.

What you’ll do

Team context

Minimum qualifications

Nice to have

To apply

Please submit your resume along with a brief cover letter that includes a “Statement of Exceptional Work.” In your cover letter, highlight one of your most impactful projects by addressing the following :

This will help us better understand your approach to solving complex problems and the value you bring to the team.

Please do not include any proprietary or confidential information in your submission

Our Interview Practices

Compensation :

$157,900.00 - $282,100.00 USD

Additional Information :

Wolters Kluwer offers a wide variety of competitive benefits and programs to help meet your needs and balance your work and personal life, including but not limited to : Medical, Dental, & Vision Plans, 401(k), FSA / HSA, Commuter Benefits, Tuition Assistance Plan, Vacation and Sick Time, and Paid Parental Leave. Full details of our benefits are available upon request.