Pharmacometrics Senior Manager

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Pharmacometrics Senior Manager

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Gilead Sciences

At Gilead, we’re creating a healthier world for all people. For more than 35 years, we’ve tackled diseases such as HIV, viral hepatitis, COVID-19 and cancer – working relentlessly to develop therapies that help improve lives and to ensure access to these therapies across the globe. We continue to fight against the world’s biggest health challenges, and our mission requires collaboration, determination and a relentless drive to make a difference.

Job Description

Director, Pharmacometrics You will lead quantitative analyses in the Oncology, Inflammation and Virology Therapeutic Areas of Gilead Sciences, Inc.. These analyses will include all stages of drug development from first‑in human through Phase IV clinical trials. You will be responsible for the conduct as well as interpretation and reporting of the analyses, and support of regulatory filings. You will champion model‑informed drug development (MIDD) across drug discovery and development and serve as a subject matter expert for modeling and simulation to cross‑functional partners.

Responsibilities

Leading quantitative and innovative strategies within clinical pharmacology to impact MIDD during the life cycle of the program

Evaluate and apply state‑of‑the‑art quantitative pharmacology approaches for clinical pharmacology decision‑making and for global regulatory submissions, including INDs, IBs, NDAs, BLAs, MAAs, and pediatric plans in collaboration with key stakeholders

Evaluate and apply strategy and content as appropriate

Guide dose regimen / optimization strategies in partnership with other therapeutic area leads and clinical pharmacology leads to enable data‑driven decisions

Develop high‑quality modeling and simulation strategy and content : author / review / approve modeling and simulation analysis plans and outputs, interpretation, and presentation of key findings to regulators and to stakeholders as needed

Ensure adherence to agreed timelines and budgets to ensure prompt and accurate execution of deliverables from clinical pharmacology studies and programs

Develop and present training within and outside the department as needed

Basic Requirements

PhD or equivalent degree in engineering, pharmaceutical sciences, pharmacology, or related discipline with 0+ years’ relevant pharmacometrics research or development experience OR

Masters or equivalent degree in engineering, pharmaceutical sciences, pharmacology, or related discipline with 6+ years’ relevant pharmacometrics research or development experience OR

Bachelors or equivalent degree in engineering, pharmaceutical sciences, pharmacology, or related discipline with 8+ years’ relevant pharmacometrics research or development experience

Preferred Requirements

Significant experience working on, with, and leading cross‑functional project / program teams in life sciences

Extensive experience in pharmacometrics leading and authoring modeling and simulation plans and having responsibility for the scientific execution of related analyses across Phase I – IV studies

Demonstrated excellence in effectively managing multiple pharmacometrics analyses deliverables and priorities through matrix management and leadership

Relevant experience in the Oncology, Virology, and / or Inflammation Therapeutic Areas

Proficiency in mathematics

Demonstrated ability to be a fast learner

Demonstrated ability to be flexible and adaptable to change

Recognized for sustained scientific excellence

Extensive knowledge of quantitative analyses as well as the physiological / pharmacological aspects of drugs

Strong communication and organizational skills

Demonstrable abilities to effectively communicate project direction and status to varying organizational levels, including leadership teams and executives

When needed, ability to travel

Benefits

The salary range for this position is : $146,540.00 - $189,640.00. Gilead considers a variety of factors when determining base compensation, including experience, qualifications, and geographic location. These considerations mean actual compensation will vary. This position may also be eligible for a discretionary annual bonus, discretionary stock‑based long‑term incentives (eligibility may vary based on role), paid time off, and a benefits package. Benefits include company‑sponsored medical, dental, vision, and life insurance plans

For Additional Benefits Information, Visit https : / / www.gilead.com / careers / compensation-benefits-and-wellbeing

Eligible employees may participate in benefit plans, subject to the terms and conditions of the applicable plans.

Gilead Sciences Inc. is committed to providing equal employment opportunities to all employees and applicants for employment, and is dedicated to fostering an inclusive work environment composed of diverse perspectives, backgrounds, and experiences. Employment decisions regarding recruitment and selection will be made without discrimination based on race, color, religion, national origin, sex, age, sexual orientation, physical or mental disability, genetic information or characteristic, gender identity and expression, veteran status or other non‑job related characteristics or other prohibited grounds specified in applicable federal, state and local laws. In order to ensure reasonable accommodation for individuals protected by Section 503 of the Rehabilitation Act of 1973, the Vietnam Era Veterans' Readjustment Act of 1974, and Title I of the Americans with Disabilities Act of 1990, applicants who require accommodation in the job application process may contact ApplicantAccommodations@gilead.com for assistance. For more information about equal employment opportunity protections, please view the 'Know Your Rights' poster. NOTICE : EMPLOYEE POLYGRAPH PROTECTION ACT YOUR RIGHTS UNDER THE FAMILY AND MEDICAL LEAVE ACT Gilead Sciences will not discharge or in any other manner discriminate against employees or applicants because they have inquired about, discussed, or disclosed their own pay or the pay of another employee or applicant. However, employees who have access to the compensation information of other employees or applicants as a part of their essential job functions cannot disclose the pay of other employees or applicants to individuals who do not otherwise have access to compensation information, unless the disclosure is (a) in response to a formal complaint or charge, (b) in furtherance of an investigation, proceeding, hearing, or action, including an investigation conducted by the employer, (c) consistent with the legal duty to furnish information; or (d) otherwise protected by law. Our environment respects individual differences and recognizes each employee as an integral member of our company. Our workforce reflects these values and celebrates the individuals who make up our growing team. Gilead provides a work environment free of harassment and prohibited conduct. We promote and support individual differences and diversity of thoughts and opinion.

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