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Sr. Manager/Associate Director, Chemistry
Sr. Manager/Associate Director, ChemistryCorvus Pharmaceuticals, Inc. • San Francisco, CA, United States
Sr. Manager / Associate Director, Chemistry

Sr. Manager / Associate Director, Chemistry

Corvus Pharmaceuticals, Inc. • San Francisco, CA, United States
1 day ago
Job type
  • Full-time
Job description

Department / Group : Chemistry

Location : South San Francisco, CA

Position Type : Full time

Role and Responsibilities

  • Independently design synthetic strategies and use those strategies to synthesize and characterize precursor compounds, starting materials, intermediates, reference compounds, and new chemical entities
  • Design small‑molecule drug candidates based on in vitro and in vivo biological activity, ADME / PK, physicochemical and IP‑relevant data.
  • Purify and characterize molecules with standard analytical techniques (e.g. HPLC, LCMS, NMR)
  • Use computation and structural data and information to design molecules
  • Perform research and / or development in collaboration with others in chemistry and biology; make detailed observations and analyze data.
  • Prepare batch records, technical reports, summaries, protocols and quantitative analyses
  • Write and review manuscripts for publication
  • Provide support in corporate research and development of patent applications
  • Develop strategies to ensure effective achievement of scientific objectives
  • Use skills to contribute to development of company objectives and principles and to achieve goals in creative and effective ways
  • Exercise independent judgment in selecting methods, techniques and evaluation criteria for obtaining results

Qualifications and Education Requirements

  • PhD in Chemistry plus 5+ years of related experience in pharmaceutical or biotechnology industry or equivalent.
  • Demonstrated expertise in synthetic organic chemistry
  • Must possess expert knowledge of scientific principles and concepts.
  • A solid understanding of modern analytical techniques (NMR, HPLC, MS)
  • Excellent verbal and written communication skills and the ability to collaborate effectively within a multidisciplinary team
  • Preferred Skills

  • Experience in designing and synthesizing PROTACs or molecular glues is strongly preferred
  • Molecular modeling and computational methods
  • Ability to manage outside vendor collaborations
  • Flexibility and willingness to solve problems that fall outside of immediate area of expertise
  • Work independently in an interdisciplinary, fast‑paced, often changing environment.
  • Committed to the values of integrity, accountability, transparency, and drive.
  • #J-18808-Ljbffr

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