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Senior Medical Director

Senior Medical Director

Astrix TechnologyBoston, MA, United States
30+ days ago
Job type
  • Full-time
Job description

Senior Medical Director

Clinical

Boston, MA, MA, US

Pay Rate Low : 220000 | Pay Rate High : 250000

  • Added - 28 / 05 / 2025

Apply for Job

We are partnered with a cutting edge biotech organization in a search for a Senior Medical Director focused in clinical development, who will lead the clinical development execution for their cardiovascular therapeutic program. This is a great chance to join a promising early stage organization and continue as a leader within clinical development.

Key Responsibilities

  • Lead the clinical development strategy for RNA-based therapies targeting hypertrophic cardiomyopathy (HCM).
  • Apply expertise in RNA science and translational research to shape clinical programs.
  • Develop and execute precision medicine strategies using innovative RNA technologies.
  • Ensure clinical initiatives are aligned with organizational goals and scientific advancements.
  • Design and direct early-phase clinical trials, including first-in-human studies.
  • Act as medical lead and monitor, maintaining focus on patient safety and treatment efficacy.
  • Drive biomarker strategy, including RNA, genomic, proteomic, and imaging-based markers.
  • Contribute to global regulatory submissions (e.g., INDs, CTAs) and provide medical input in alignment with FDA, EMA, and ICH guidelines.
  • Collaborate with cross-functional teams, including preclinical, clinical operations, and regulatory affairs, to integrate and execute clinical strategy.
  • Represent the organization in scientific forums such as advisory boards, steering committees, and DSMBs.
  • Engage with key opinion leaders to guide clinical direction and validate development plans.
  • Continuously evaluate emerging scientific literature to inform strategy and innovation.
  • Support regulatory planning and documentation efforts for RNA-targeted therapeutic programs worldwide.
  • Ensure adherence to international clinical development and regulatory standards.

    • Qualifications

  • MD or MD / PhD with specialization in cardiovascular medicine.
  • At least 5 years of experience in translational or clinical cardiovascular research; prior work in HCM is a strong plus.
  • Proven track record in leading clinical development of RNA-based or genetic therapies.
  • Board Certification or substantial clinical experience in HCM or related cardiovascular conditions strongly preferred.

    • Base Salary : $220-$250k / yr

  • Will be an onsite position sitting in either the Boston or San Diego area

    • This job description is a complete list of all desired skills, but not all are required. We strongly encourage candidates who have some of the skills to apply. We look forward to a conversation to learn more about you!

    We are an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion, sex, national origin, disability status, protected veteran status, or any other characteristic protected by law.

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