Talent.com
Principal Investigator
Principal InvestigatorMetric • New Bedford, MA, US
Principal Investigator

Principal Investigator

Metric • New Bedford, MA, US
6 hours ago
Job type
  • Full-time
Job description

Job Description

Opportunity : Principal Investigator (General Medicine)

Metric Bio is partnering with a high-performing and rapidly expanding clinical site network based in Massachusetts, in the search for an accomplished Principal Investigator specialising in General Medicine . This is a unique opportunity to lead meaningful clinical research, drive innovation, and directly impact patient outcomes within a cutting-edge US-based organisation.

The Role :

As the Principal Investigator, you will provide expert medical leadership across multiple clinical trials, ensuring scientific integrity, regulatory compliance, and the highest standards of patient safety. You’ll be a key contributor in shaping research strategy, guiding clinical teams, and building strong collaborations with sponsors and stakeholders.

Key Responsibilities

  • Serve as the lead Principal Investigator across general medicine clinical trials
  • Oversee all aspects of study conduct, ensuring alignment with protocol, GCP, and FDA standards
  • Conduct medical evaluations, determine eligibility, and monitor patient safety
  • Provide expert input into feasibility assessments and study design
  • Safeguard data quality and ethical integrity across trials
  • Develop and maintain strong sponsor and regulator relationships
  • Mentor and support Sub-Investigators and research teams
  • Champion clinical excellence and continuous process improvement

Required Qualifications & Experience

  • MD / DO with active and unrestricted US medical license.
  • Minimum 5 years’ post-licensure experience in general or internal medicine
  • Direct involvement in 10 or more clinical trials (Phase II–IV preferred) as Principal Investigator or Sub-Investigator.
  • Deep understanding of GCP, FDA regulations, ICH guidelines, and clinical governance
  • Proven track record in clinical leadership and decision-making
  • Excellent communication, patient-centric approach, and collaborative mindset
  • What’s on Offer

  • Competitive compensation package + comprehensive benefits
  • Opportunity to lead high-impact trials across varied therapeutic areas
  • Innovative, collaborative research environment
  • Professional development & leadership support
  • Make a significant contribution to improving future patient care
  • Interested in Applying?

    If you are an experienced physician with a passion for research leadership and meet the clinical trial experience requirement, we would love to hear from you.

    Contact Metric Bio : oli.oldham@metric-search.com

    Create a job alert for this search

    Principal Investigator • New Bedford, MA, US

    Related jobs
    Travel Psychologist - School in Brockton, MA

    Travel Psychologist - School in Brockton, MA

    AlliedTravelCareers • Brockton, MA, US
    Full-time
    AlliedTravelCareers is working with Aequor to find a qualified Psychologist - School in Brockton, Massachusetts, 02301!.School Psychologist – Pre-K Diagnostic Team. Schedule : Monday–Friday, 8 : 45 AM–...Show more
    Last updated: 1 day ago • Promoted
    Director, Medical Oncology

    Director, Medical Oncology

    Southcoast Health • Fairhaven, MA, United States
    Full-time
    Join Southcoast Health, where your future is as promising as the care we provide.Our commitment to each other, our patients, and our community is more than a mission - it's our way of life, and you...Show more
    Last updated: 30+ days ago • Promoted
    Mental Health Professional

    Mental Health Professional

    VitalCore Health Strategies Careers • Bridgewater, Massachusetts, US
    Full-time
    Join the VitalCore Team in Massachusetts!.We’re people who are fueled by passion, not by profit.VitalCore Health Strategies (VCHS), an industry leader in Correctional Health Care, has an opening fo...Show more
    Last updated: 30+ days ago • Promoted
    SLP

    SLP

    National Staffing Solutions • Somerset, MA, US
    Full-time
    Details of the SLP opening in Somerset, MA : .Anticipated Start Date : 12 / 02 / 2025.Work Setting : Skilled Nursing Facility. Anticipated Duration of Assignment : 13 Weeks.Anticipated Schedule : 5x8 Days.We`...Show more
    Last updated: 2 hours ago • Promoted • New!
    Primary Care Physician

    Primary Care Physician

    The Inline Group • Brockton, Massachusetts, US
    Full-time
    Primary Care Physician physician job in Massachusetts : The Inline Group -.Hours : Monday - Friday 8 am - 5 pm; 1 Night 11 : 30 am - 8 am. Saturdays Rotated 1 : 8 9 am - 3 pm.Compensation : - $220,000 - ...Show more
    Last updated: 30+ days ago • Promoted
    Agent

    Agent

    Pinkerton • Canton, Massachusetts, United States
    Full-time
    At Pinkerton, the mission is to protect our clients.To do this, we provide enterprise risk management services and programs specifically designed for each client. Pinkerton employees are one of our ...Show more
    Last updated: 22 hours ago • Promoted • New!
    PT

    PT

    National Staffing Solutions • New Bedford, MA, US
    Full-time
    Details of the PT opening in New Bedford, MA : .Anticipated Start Date : 11 / 24 / 2025.Work Setting : Skilled Nursing Facility. Anticipated Duration of Assignment : 13 Weeks.Anticipated Schedule : 5x8 Days.W...Show more
    Last updated: 2 hours ago • Promoted • New!
    Border Patrol Agent - Earn up to $30,000 in Recruitment Incentives

    Border Patrol Agent - Earn up to $30,000 in Recruitment Incentives

    U.S. Customs and Border Protection • New Bedford, MA, United States
    Full-time
    Customs and Border Protection (CBP) offers those interested in a career in law enforcement an exceptional opportunity to work with an elite team of highly trained professionals whose camaraderie, p...Show more
    Last updated: 8 days ago • Promoted
    Clinical Assistant / Associate Professor Tenure Track - Faculty Law School

    Clinical Assistant / Associate Professor Tenure Track - Faculty Law School

    UMass Dartmouth • Dartmouth, MA, United States
    Full-time
    UNIVERSITY OF MASSACHUSETTS SCHOOL OF LAW.Assistant / Associate Professor - Criminal Defense Clinic.The University of Massachusetts School of Law invites applications for the 2026-2027 academic year ...Show more
    Last updated: 30+ days ago • Promoted
    Physician Psychiatry-Child / Adolescent - Competitive Salary

    Physician Psychiatry-Child / Adolescent - Competitive Salary

    FCS, Inc. • New Bedford, Massachusetts, United States
    Full-time
    This is a part-time Medical Director role for the Youth Crisis Stabilization Unit! Approx 5-8 hours per week.This role can be done fully remotely!. For more information please contact Andrew McKinne...Show more
    Last updated: 30+ days ago • Promoted
    Brockton, MA SIU Investigator

    Brockton, MA SIU Investigator

    Lemieux & Associates LLC • Brockton, MA, USA
    Full-time +1
    Quick Apply
    Lemieux & Associates, a national leader in the investigative industry, is.SIU / Claims Investigators in the Brockton or surrounding area. This is a part-time position to start with the ability to ...Show more
    Last updated: 30+ days ago
    Physician Family Practice-Without OB - Competitive Salary

    Physician Family Practice-Without OB - Competitive Salary

    Palm Health Resources • Fall River, Massachusetts, United States
    Full-time +1
    Full-time Permanent Gastroenterologist Physician needed in Bristol County Mass.Perm - Full-time Gastroenterologist.Skilled : Upper and Lower Endoscopy procedures, Â Gastrointestinal diseases, and Ge...Show more
    Last updated: 30+ days ago • Promoted
    Customs and Border Protection Officer - Experienced (GS9)

    Customs and Border Protection Officer - Experienced (GS9)

    U.S. Customs and Border Protection • New Bedford, Massachusetts, US
    Full-time
    Customs and Border Protection (CBP) offers those interested in a career in law enforcement an exceptional opportunity to work with an elite team of highly trained professionals whose camaraderie, p...Show more
    Last updated: 30+ days ago • Promoted
    Mental Health Counselor

    Mental Health Counselor

    SonderMind • New Bedford, MA, US
    Full-time
    SonderMind is a leading mental health care platform revolutionizing therapy services.We are seeking compassionate and highly skilled licensed mental health therapists to join our expanding network....Show more
    Last updated: 28 days ago • Promoted
    Physician Family Practice-Without OB - Competitive Salary

    Physician Family Practice-Without OB - Competitive Salary

    Healthcare United • Somerset, Massachusetts, United States
    Full-time
    Part-Time Primary Care Physician Opportunity near Somerset, Massachusetts.Healthcare United is actively recruiting a .This part-time position offers a flexible schedule of .MD or DO in Family Medic...Show more
    Last updated: 18 hours ago • Promoted • New!
    Remote Finance Director - AI Trainer ($50-$60 / hour)

    Remote Finance Director - AI Trainer ($50-$60 / hour)

    Data Annotation • New Bedford, Massachusetts
    Remote
    Full-time +1
    We are looking for a finance professional to join our team to train AI models.You will measure the progress of these AI chatbots, evaluate their logic, and solve problems to improve the quality of ...Show more
    Last updated: 30+ days ago • Promoted
    Primary Care Physician - Practice Ownership Opportunity in Gloucester, MA

    Primary Care Physician - Practice Ownership Opportunity in Gloucester, MA

    MDVIP • New Bedford, MA, US
    Full-time
    Primary Care Physician – Practice Ownership & Succession Opportunity.Reclaim the Practice of Your Dreams.What if you could return to the heart of medicine- the kind of practice where you ...Show more
    Last updated: 30+ days ago • Promoted
    Adult Psychiatrist

    Adult Psychiatrist

    Green Key Resources • New Bedford, MA, US
    Full-time
    Full Time Days, No Weekends or On-Call Required!.As a Psychiatrist, you will have a once in a lifetime opportunity to inspire a team to deliver the quality care that originally brought you into the...Show more
    Last updated: 13 days ago • Promoted