Talent.com
(Principal) Proteomics Scientist / Investigator (San Diego)

(Principal) Proteomics Scientist / Investigator (San Diego)

EPM ScientificSan Diego, CA, US
17 hours ago
Job type
  • Part-time
Job description

About the Role

The client is an innovative early-stage biotech organization focused on accelerating drug development and advancing personalized medicine through multi-omics solutions. Leveraging cutting-edge mass spectrometry technology, advanced computational tools, and comprehensive human health data, the client enables rapid biomarker discovery at scale. This approach provides deeper insights into human biology and aligns therapeutic targets with patient populations to improve treatment precision and outcomes. The team consists of highly collaborative scientists, clinicians, and engineers committed to scientific rigor and transformative innovation.

Position Overview

We are seeking a dynamic Proteomics Principal Investigator to lead complex proteomics initiatives, foster scientific breakthroughs, and strengthen client partnerships. This role requires deep expertise in mass spectrometry-based proteomics, strong leadership capabilities, and proficiency in integrating multi-omics data to deliver actionable insights within a regulated CRO setting. The ideal candidate excels in collaborative environments, mentors high-performing teams, and sets the standard for scientific excellence.

Key Responsibilities

  • Partner with leading experts to promote growth through advanced training and knowledge-sharing.
  • Oversee project execution between the client and internal wet- and dry-lab teams, ensuring timely delivery and resolving challenges as needed.
  • Design research strategies, develop study plans, and prepare comprehensive reports.
  • Analyze mass spectrometry data, review spectra, and identify compounds.
  • Guarantee data integrity and compliance with quality and regulatory standards.
  • Compile findings into presentations and deliverables for stakeholders.
  • Manage multiple projects simultaneously, ensuring timelines and objectives are met.
  • Interpret complex scientific results and stay current with emerging technologies and literature.

Required Experience

  • Minimum 5 years in CRO, pharmaceutical, or biotech environments with hands-on experience in LC-MS / MS platforms (Orbitrap, Q-TOF, timsTOF) and data analysis workflows (DDA, DIA, PRM, MRM / SRM, TMT / iTRAQ, PTM).
  • At least 5 years in a leadership role managing scientific teams and projects.
  • Demonstrated ability to design and execute advanced proteomics experiments (discovery, targeted, PTM analysis).
  • Proven track record in client-facing roles, scientific presentations, and cross-functional collaboration.
  • Qualifications

  • PhD / MD in a relevant discipline (chemistry, biochemistry, biology, pharmacology, or related life sciences) or equivalent experience. BS + 10 years or MS + 5 years relevant experience.
  • Strong background in mass spectrometry-based proteomics and data interpretation.
  • Experience with metabolomics and proteomics methodologies.
  • Skilled in managing multiple priorities, mentoring teams, and delivering results under tight timelines.
  • Ability to communicate complex scientific concepts clearly in both written and verbal formats.
  • Collaborative mindset with experience working alongside multidisciplinary teams.
  • Detail-oriented with a commitment to accuracy and reliability.
  • Up-to-date knowledge of precision medicine advancements.
  • Role Impact

    This is a client-facing leadership position, serving as a strategic partner to laboratory operations. The role involves managing 15+ client programs, contributing to study design, developing project plans, and ensuring seamless communication between clients and internal teams to deliver transformative biological insights across diverse therapeutic areas.

    Create a job alert for this search

    Principal San Diego • San Diego, CA, US

    Related jobs
    • Promoted
    Freelance Biology Quality Assurance

    Freelance Biology Quality Assurance

    VirtualVocationsEscondido, California, United States
    Full-time
    A company is looking for a Freelance Biology Quality Assurance (AI Trainer).Key Responsibilities Create and refine content to ensure accuracy and relevance in Biology Assess qualification tests ...Show moreLast updated: 1 day ago
    • Promoted
    Senior Scientist I - Neuroscience

    Senior Scientist I - Neuroscience

    Novartis Group CompaniesLa Jolla, CA, United States
    Full-time
    We are seeking an enthusiastic, highly motivated, results-oriented Senior Scientist I to join our Genetics Medicine Unit. The ideal candidate will be innovative, organized, and adaptable to a fast-p...Show moreLast updated: 30+ days ago
    • Promoted
    Data Scientist, Trust & Safety

    Data Scientist, Trust & Safety

    VirtualVocationsEscondido, California, United States
    Full-time
    A company is looking for a Data Scientist, Trust & Safety.Key Responsibilities Facilitate a zero-friction approach to email sending Investigate anomalies and gang attacks to identify root causes...Show moreLast updated: 1 day ago
    • Promoted
    Research Assistant II - Laboratory of Dr. Sreekanth Chalasani

    Research Assistant II - Laboratory of Dr. Sreekanth Chalasani

    Salk Institute for Biological StudiesLa Jolla, CA, United States
    Full-time
    The Salk Institute is seeking a Research Assistant with expertise in neuronal cultures, viral handling or ultrasound techniques to support ongoing research in ultrasound-controlled cellular manipul...Show moreLast updated: 30+ days ago
    • Promoted
    Project Biologist

    Project Biologist

    Bio-Studies Inc.San Diego, CA, US
    Full-time
    Bio-Studies is a growing natural resources consulting firm in Southern California providing quality natural resources consulting services to a diversity of clientele.Our team of biologists off...Show moreLast updated: 5 days ago
    • Promoted
    Research Scientist - Laboratory of Dr. Sreekanth Chalasani

    Research Scientist - Laboratory of Dr. Sreekanth Chalasani

    Salk Institute for Biological StudiesLa Jolla, CA, United States
    Full-time
    The Salk Institute is seeking a highly skilled Research Scientist with extensive experience in tissue culture, gene delivery systems, and ultrasound-mediated mechanotransduction.The successful cand...Show moreLast updated: 30+ days ago
    • Promoted
    Principal Manufacturing & Autonomy Research Scientist

    Principal Manufacturing & Autonomy Research Scientist

    LeidosRancho Santa Fe, CA, US
    Full-time
    Are you a motivated Principal Resilient Systems Scientist with a technical vision and hands-on knowledge of mission-focused systems? The Leidos Innovations Center’s newly established Informat...Show moreLast updated: 12 days ago
    • Promoted
    QC Chemist

    QC Chemist

    Novartis Group CompaniesCarlsbad, CA, United States
    Full-time
    The QC Chemist will support all technical aspects related to quality control testing readiness, including QC reagents and materials management, equipment preparation and daily cleaning and maintena...Show moreLast updated: 30+ days ago
    • Promoted
    Scientist

    Scientist

    QuidelOrthoSan Diego, CA, United States
    Full-time
    QuidelOrtho unites the strengths of Quidel Corporation and Ortho Clinical Diagnostics, creating a world-leading in vitro diagnostics company with award-winning expertise in immunoassay and molecula...Show moreLast updated: 30+ days ago
    • Promoted
    Stormwater Scientist (QSD)

    Stormwater Scientist (QSD)

    Bancroft Construction Services, LLCSan Diego, CA, US
    Full-time
    Bancroft Construction Services specializes in delivering environmentally responsible construction solutions that balance infrastructure development with ecological protection.We are seeking a Quali...Show moreLast updated: 27 days ago
    • Promoted
    QC Microbiologist

    QC Microbiologist

    Novartis Group CompaniesCarlsbad, CA, United States
    Full-time
    The QC Microbiologist supports all technical aspects related to quality control testing readiness, including QC reagents and materials management, equipment preparation and daily cleaning and maint...Show moreLast updated: 30+ days ago
    • Promoted
    Research Assistant II - Laboratory of Dr. Sreekanth Chalasani

    Research Assistant II - Laboratory of Dr. Sreekanth Chalasani

    InsideHigherEdLa Jolla, California, United States
    Full-time
    The Salk Institute is seeking a Research Assistant with expertise in neuronal cultures, viral handling or ultrasound techniques to support ongoing research in ultrasound-controlled cellular manipul...Show moreLast updated: 30+ days ago
    • Promoted
    Clinical Affairs Scientist

    Clinical Affairs Scientist

    VirtualVocationsEscondido, California, United States
    Full-time
    A company is looking for a Clinical Affairs Scientist.Key Responsibilities Provide thought leadership on clinical topics to support strategy development and execution Generate content for extern...Show moreLast updated: 6 days ago
    • Promoted
    Biostatistician

    Biostatistician

    VirtualVocationsEscondido, California, United States
    Full-time
    A company is looking for a Biostatistician.Key Responsibilities Contribute to the design, analysis, and reporting of clinical trials or scientific research studies Identify and report data issue...Show moreLast updated: 30+ days ago
    • Promoted
    Senior Scientist in Computational Biology

    Senior Scientist in Computational Biology

    VirtualVocationsChula Vista, California, United States
    Full-time
    A company is looking for a Senior Scientist - Research Computational Biology (ARIA).Key Responsibilities Extract biological insights from complex omics and screening data to characterize disease ...Show moreLast updated: 1 day ago
    • Promoted
    Research Scientist - Laboratory of Dr. Sreekanth Chalasani

    Research Scientist - Laboratory of Dr. Sreekanth Chalasani

    InsideHigherEdLa Jolla, California, United States
    Full-time
    The Salk Institute is seeking a highly skilled Research Scientist with extensive experience in tissue culture, gene delivery systems, and ultrasound-mediated mechanotransduction.The successful cand...Show moreLast updated: 30+ days ago
    • Promoted
    Generative AI Scientist

    Generative AI Scientist

    VirtualVocationsEscondido, California, United States
    Full-time
    A company is looking for a Generative AI Scientist.Key Responsibilities Deliver solutions to identify payment integrity issues and improve healthcare quality Develop exploratory data analysis ap...Show moreLast updated: 1 day ago
    • Promoted
    Principal Scientist, Comparative Medicine- Research Collaborations

    Principal Scientist, Comparative Medicine- Research Collaborations

    Novartis Group CompaniesLa Jolla, CA, United States
    Full-time
    Influences and drives projects using broad, up-to-date knowledge of a.Uses broad understanding of the project and leads own team through collaboration, curiosity and connects team to matrix and pro...Show moreLast updated: 14 days ago
    • Promoted
    Study Coordinator

    Study Coordinator

    VirtualVocationsEscondido, California, United States
    Full-time
    A company is looking for a Study Coordinator to support toxicology studies in San Diego, CA.Key Responsibilities Manage project and study timelines using the Planisware project management system ...Show moreLast updated: 2 days ago
    • Promoted
    Senior ML Scientist

    Senior ML Scientist

    VirtualVocationsEscondido, California, United States
    Full-time
    A company is looking for a Senior ML Scientist to develop automated methods for tagging data collected by autonomous vehicles. Key Responsibilities Design, implement, and deploy machine learning m...Show moreLast updated: 1 day ago