Director / Sr. Director, Inflammation

The heart of Prellis Bio strategy is the combination of novel, cutting edge methods in machine learning, biology at scale and next gen antibody discovery that address key bottlenecks in the drug development pipeline. To accomplish that, we are putting together an incredible team of discovery biologists, computational scientists, and protein scientists who want to make a difference to this important problem. In this leadership role, you will help build the Inflammation therapeutic area (TA), hire and manage staff.

You will report to the CSO and work a hybrid schedule at our headquarters in Berkeley, CA.

Your primary responsibilities will include

Contribute to Prellis Bio strategy in autoimmune & immunology therapeutic areas addressable by large molecule or complex modalities

Work cross-functionally as aproject team leadto design, experiments, high-throughput experimental assays and machine learning models to help deconvolute these biologies

Support identification and validation of high-value, disease-modifying therapeutic targets through literature-based evaluations

Lead efforts and partner with our statistical genetics and machine learning teams to follow up on these targets with the goal of producing viable therapeutic interventions

Move with the project as it moves into the clinic and provide clinical support and work closely with our clinical groups and chief medical officer.

Lead external collaborations with partners and with other organizations and individuals in efforts related to the Inflammation & Immunology area.

You will join a growing and well-positioned biotech startup that is very much in formation. Anticipate a lot can change in this early and exciting phase, providing many opportunities for significant impact. You will work with a very experienced leadership team, learn a broad range of skills, and help shape Prellis Bio's culture, strategic direction, and outcomes. Join us, and help make a difference to patients!

About You

PhD in inflammation, autoimmune and / or immunology with 10 years of experience in target / drug discovery in industry or academia.

A scientific track record in inflammation & autoimmune disease with a focus on large molecule (e.g.antibody) modalities

Familiarity with interpreting RNA-seq and protein expression data, translational and preclinical in vitro and in vivo data, and clinical trial results

Demonstrated track record in building partnerships or collaborations with data scientists or computational biologist, engineers and experimental biologists

Experience in basic research, translational biology and supporting inflammation & immunology clinical development

Contribution to the preparation of patents, documentation for IND filings, and publications.

Experience leading a high-performance team, including goal setting, and contributing to a culture of high-quality methods development and reducing those methods to a practical implementation

Communicate effectively and collaborate with people of diverse backgrounds and job functions, including a track record of collaborating with life scientists

Passion for making a difference in the world

About Prellis Biologics

At Prellis we integrate human biology with machine learning. We aim to revolutionized drug discovery by harnessing the power of human immune system with tightly, integrated machine learning to develop next-generation antibody therapeutics with unparalleled speed, precision and safety. We are committed to empowering our pharmaceutical partners with access to the most promising fully human body candidate rapidly identified from the human immune repertoire, enabling them to bring life-changing treatments to patients faster than ever before.Prellis Biologics is a pre-IPO biotech located in Berkeley CA with a team-oriented, inclusive, and family-friendly culture. Our growing pipeline target high unmet patient needs across therapeutics including metabolic, inflammation, and oncology disease. Prellis has raised funding from top investors, including Celesta, Khosla Ventures, SOSV, & Avidity Partners.

What you can expect of us

As we work to develop treatments that take care of others, we also work to care for your professional and personal growth and well-being. From our competitive benefits to our collaborative culture, we'll support your journey every step of the way.

The expected annual salary range for this role in the U.S. is posted. Actual salary will vary based on several factors including but not limited to, relevant skills, experience, and qualifications.

In addition to the base salary, Prellis offers compelling benefits based on eligibility, comprising of health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work / life balance, and career development opportunities that may include :

A competitive employee benefits package, including group medical, dental and vision coverage, life and disability insurance, flexible spending accounts an a 401(k) plan

Stock-based long term incentive

Holiday package including a 1+ week winter shutdown

Flexible work models, including remote and hybrid working arrangements, where possible

Prellis does not have an application deadline for this position; we will continue accepting applications until we receive a sufficient number or select a candidate for the position.

Prellis Bio is an equal opportunity employer. All applicants will be considered for employment without attention to race, color, religion, sex, sexual orientation, gender identity, national origin, veteran or disability status.

We believe diversity, equity, and inclusion need to be at the foundation of our culture. We work hard to bring together diverse teams–grounded in a wide range of expertise and life experiences–and work even harder to ensure those teams thrive in inclusive, growth-oriented environments supported by equitable company and team practices. All candidates can expect equitable treatment, respect, and fairness throughout the interview process.

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