Responsibilities Preparation of prototype formulations (solutions, suspensions, tablets, capsules, powder blends, semi-solid dosage forms, sterile and non-sterile liquids) for exploratory studies in in-vitro and in-vivo models Development of oral, topical and intravenous (sterile) dosage forms for feasibility studies and small scale manufacturing operations Measurement of key active compound and formulation properties (such as solubility, tablet hardness, disintegration, pH, isotonicity, gelling tendency, etc.) Assessment of the chemical and physical stability of prototype formulations, as well as the performance of prototype formulations using in-vitro tests (non-sink dissolution, precipitation, etc.) Identify potential stability and performance issues with prototype formulations Development of protocols for preparation of formulations at preclinical and clinical study sites Qualifications Experience with drug formulation and pre-formulation techniques, and an understanding of drug candidate properties Experience with amorphous solid dispersions (spray dried dispersions or hot melt extrusion) and modified release tablet design. Basic chemistry (wet or solid state) laboratory experience. Experience working with laboratory equipment, mechanically inclined. Experience with more advanced characterization techniques such as Raman, thermal analysis and dissolution. Ability to follow procedures reliably and consistently, Strong computer and organizational skills Adept in Microsoft office Mathematical or Mechanistic Modeling Excellent communication (oral and written) and attention to detail Ability to work independently and as part of a team, self-motivated, adaptable, and a positive attitude Ability to learn new techniques, keep accurate records, follow instructions, and comply with company policies Benefits and Additional Information The position is full-time, Monday through Friday, 8am-5 pm May be requested to work on weekends, overtime, and holidays based on business needs. Candidates currently living within a commutable distance of Groton, CT are encouraged to apply. Ability to work overtime as required. Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options Life and insurance 401(k) with company match Paid vacation and holidays #LI-EB1 Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer. #J-18808-Ljbffr
Associate Formulations Scientist in Groton • Groton, MA, United States
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