Clinical Trial Lead

Clinical Trial Lead

Hybrid / Full Time / Chesterbrook, PA

At Novocure, we're working to extend the lives of patients battling some of the most aggressive cancers. Every role here contributes to that mission—and as Clinical Trial Lead, you'll lead the strategic planning, execution, and successful delivery of global outsourced clinical trials that advance innovative therapies for patients.

ABOUT THE ROLE

We are seeking an experienced Clinical Trial Lead to oversee global clinical studies outsourced to Contract Research Organizations (CROs). This role serves as the primary sponsor representative responsible for leading cross-functional study teams, managing CRO performance, overseeing timelines and budgets, mitigating risks, and ensuring studies are executed in compliance with regulatory requirements and quality standards. You'll work independently while partnering with colleagues across Clinical Operations, Medical, Regulatory, Data Management, Biostatistics, Finance, and external vendors.

WHAT YOU'LL DO

• Lead cross-functional Clinical Study Teams from study startup through closeout.
• Serve as the primary liaison between Novocure and CRO partners.
• Oversee study timelines, milestones, deliverables, and risk mitigation plans.
• Manage study budgets, change orders, invoices, and financial performance.
• Monitor CRO and vendor performance to ensure quality and compliance.
• Support protocol development, feasibility assessments, and study planning.
• Track KPIs and proactively resolve operational challenges.
• Support database lock, clinical study reports, audits, inspections, and regulatory submissions.
• Partner with global colleagues across North America, Europe, and Israel.

ABOUT YOU

You are an experienced clinical operations professional who thrives in complex global studies. You can independently lead outsourced trials, influence cross-functional teams without direct authority, anticipate risks before they become problems, and balance quality, timelines, and budgets while keeping patients at the center of every decision.

Minimum Qualifications

• Bachelor's degree in Life Sciences, Nursing, Pharmacy, or a related field.
• 5–7+ years of clinical research experience, including 2–3+ years leading global clinical studies.
• Experience leading studies from startup through closeout.
• Experience managing CROs, vendors, study budgets, and project timelines.
• Strong knowledge of ICH-GCP, FDA, EMA, and global regulatory requirements.
• Excellent leadership, communication, and project management skills.

Preferred Qualifications

• Oncology clinical trial experience strongly preferred.
• Experience leading other highly complex global studies.
• Experience with CTMS, eTMF, and EDC systems.
• Advanced degree (MS, PharmD, or PhD).

HOW YOU'LL WORK

• Hybrid role supporting our Chesterbrook, PA office.
• Collaborate regularly with global colleagues across Europe and Israel.
• Flexibility to support occasional early-morning meetings across time zones.
• Approximately 10–20% travel as business needs require.

WHAT WE OFFER

The pay range which Novocure expects to pay for this role at the time of this posting is $147,000 - $190,000/yr. This position is also eligible for an annual incentive bonus and restricted stock unit grant in addition to a full range of benefits. Individual compensation within this range depends on a variety of factors, including, but not limited to, prior education and experience, job-related knowledge and skills demonstrated.

ABOUT NOVOCURE

Novocure is a company with a powerful mission, to extend the lives of people living with some of the most aggressive forms of cancer. Here your work will have a direct impact on patients and those who care about them. Join a team of passionate, collaborative people who support each other, challenge one another, and innovate together. Here, you’ll connect, grow, and make a real difference. We’re a company with the drive of a startup and the strength that comes with 25 years of success.

Novocure operates at a rare crossroad, where advanced medical technology converges with cutting-edge biotechnology. We are the only company to develop and commercialize Tumor Treating Fields (TTFields), a proprietary, groundbreaking therapy designed to disrupt cancer cell division. With us you will find a unique combination of laboratory research work alongside engineering development of advanced technologies. This fusion of disciplines positions us as true pioneers in oncology innovation, leading a new frontier in the treatment of aggressive cancers.

Our patient-forward values

– innovation

– focus

– drive

– courage

– trust

– empathy

#LI-RJ1

Novocure is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state, or local law. We actively seek qualified candidates who are protected veteran and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Novocure is committed to providing an interview process that is inclusive of our applicant’s needs. If you are an individual with a disability and would like to request an accommodation, please email

If you're excited about this role, please apply.