Arrowhead Pharmaceuticals, Inc. (Nasdaq ARWR) is a commercial stage biopharmaceutical company that develops medicines that treat intractable diseases by silencing the genes that cause them. Using a broad portfolio of RNA chemistries and efficient modes of delivery, Arrowhead therapies trigger the RNA interference mechanism to induce rapid, deep, and durable knockdown of target genes. RNA interference, or RNAi, is a mechanism present in living cells that inhibits the expression of a specific gene, thereby affecting the production of a specific protein. Arrowhead's RNAi-based therapeutics leverage this natural pathway of gene silencing. Arrowhead is focused on developing innovative drugs for diseases with a genetic basis, typically characterized by the overproduction of one or more proteins that are involved with disease. The depth and versatility of our RNAi technologies enables us to potentially address conditions in virtually any therapeutic area and pursue disease targets that are not otherwise addressable by small molecules and biologics. Arrowhead is leading the field in bringing the promise of RNAi to address diseases outside of the liver, and our clinical pipeline includes disease targets in the liver and lung with a promising pipeline of preclinical candidates. Arrowhead's corporate headquarters is in Pasadena, CA with research and development teams in Madison, WI & San Diego, CA, and a state of the art manufacturing facility in Verona, WI. Our employees are nimble, science-driven innovators who are collaborating to bring new therapies to patients in need. The Position A Scientist I, Late Phase Process Development works within the CMC department on small molecule and conjugation chemistry to generate knowledge and documents to support late phase process development and regulatory filings. Responsibilities Oversee and perform experiments for late phase process development of API and regulated materials, including process improvement, impurity identification, and fate and purge studies Analyze and interpret experimental technical data Work with internal and external teams to manage the determination, supply, and specifications of materials for Arrowhead's late phase drug substance programs Maintain knowledge of process and project history as well as process development and regulatory issues Collaborate with Regulatory Affairs in the preparation of regulatory documents, including CTAs, IMPDs, NDAs, and MAAs. Make oral presentations to scientists and management Guide, mentor and develop chemists across the team Support talent acquisition efforts Identify growth opportunities for team members to reach their full potential Work closely with other department members Recommend new ideas, synthetic routes, and technologies to support departmental goals Requirements Master's Degree in Chemistry with at least 5 years work experience or Bachelor's Degree in Chemistry with at least 8 years equivalent industry work experience Excellent verbal and written communication skills Excellent problem-solving skills Knowledge in synthetic chemistry and analytical technology, hands-on experience in syntheses and development of small molecule and large molecule drug candidates Preferred Strong track record of scientific publication Prior experience with cGMP manufacturing and pharmaceutical regulatory compliance Prior experience working with or within CDMOs Wisconsin pay range $85,000-$95,000 USD Arrowhead provides competitive salaries and an excellent benefit package. Candidates must have current, valid authorization to work in the country where this role is located. California Applicant Privacy Policy #J-18808-Ljbffr
Scientist I, CMC Process Development • Verona, WI, United States
This is a fully onsite role based at our GMP Laboratory in Middleton, WI.We welcome applicants from all locations within the US.Please note that relocation assistance is not provided for this posit... Show more
Company:Sabrosura Foods is one of the leading marketers of Hispanic products sold throughout the U.El Viajero, Reynaldo's, La Morenita, Caribe, and Bio Salud!.Sabrosura Foods is also one of the lar... Show more
JOB SUMMARY: The general laborer provides production support by running machines and ensuring a safe work environment.DUTIES & RESPONSIBILITIES: Under general supervision, performs ... Show more
Our client is a well-established contract manufacturer producing a range of electro-mechanical assemblies including but not exclusive to sub-fractional horsepower motors, wire-harnesses, plastics, ... Show more
Sherwin-Williams Management & Sales Training Program.The Sherwin-Williams Management & Sales Training Program is an accelerated, entry-level position designed to prepare you for a Store Management ... Show more
Production & Inventory Control Manager.ETC is seeking an experienced and people-focused Production & Inventory Control Manager to lead our planning and inventory functions while developing a high-p... Show more
Oceanography (OCEANO) Officers, also called METOC, are the Navy's geophysical experts who understand and apply all facets of meteorology, oceanography, hydrography, bathymetry, geophysics, and prec... Show more
Do you enjoy finding answers when things don't add up? Put your analytical skills to work investigating inventory issues and driving meaningful improvements.We have an openings for Inventory Contro... Show more
At ProMach, we're looking for people who want to shine.You'll have opportunities to take your career in the direction you want.You'll be challenged and rewarded.Improve our customers' packaging per... Show more
New Hires eligible for $2,000 Sign-On Bonus! 1st Shift Position:7:30am - 4:00pm, Mon - FriPosition Overview:The primary purpose of the QC Analytical Chemist is to provide support to the Production... Show more
We are seeking a skilled and reliable Forklift Operator to join our team.The ideal candidate will be responsible for operating a forklift to move, locate, relocate, stack, and count merchandise wit... Show more
Manufacturing Engineering Manager.Standex International is a global industrial growth company operating through our market-leading brands in electronics, cutting-edge forming technologies, engravin... Show more
DescriptionWe are looking for a Machinist 3 to join our 100% EMPLOYEE-OWNED team.Second Shift:Monday-Thursday 2:00pm- 12:30amLatitude Corp.We embrace problem solvers, creativity and innovation.With... Show more
Flexible scheduling with a side of always feeling valued.A job at McDonald's offers a job combo that fits you.Previous leadership experience is preferred, ideally within a restaurant, retail, or ho... Show more
Senior Product Development & Sourcing Manager.The Senior Product Development & Sourcing Manager drives global sourcing strategies to deliver optimal value, quality, cost-efficiency, and on-time del... Show more
Work ScheduleSecond Shift (Afternoons)Environmental ConditionsAdherence to all Good Manufacturing Practices (GMP) Safety Standards, Laboratory Setting, Office, Some degree of PPE (Personal Protecti... Show more
Excellent opportunity to join a leading, national credit card processing company that has over a decade of industry experience.Slice Merchant Services offers innovative payment processing solutions... Show more
Commercial Construction and Farm Equipment Lead – Lead Field Operations for KOENECKE EQUIPMENT INC.Company: KOENECKE EQUIPMENT INC.Salary/Pay Rate: $30 to $35 per hour plus Performance and Sign-on ... Show more
Shaffer Trucking offers a Regional for CDL A Drivers in the Midsouth 21 Days Out.One-year verifiable tractor trailer experience with a class A CDL. Show more
Earn up to $400/week, depending on the number and type of studies you complete.Share honest feedback on products and services from independent brands.Assignments include short online surveys (10–20... Show more
