Work Details :
Provides technical experience needed to assist in studying the basic principles of plant and animal life
Work with staff on performing various experiments and procedures related to differentiation and phenotyping of induced pluripotent stem cell lines, 1
Perform standard immunological techniques, including western blotting and immunostaining 2
Operate laboratory equipment to analyze samples 3
Analyze laboratory findings
Train staff on the proper usage of laboratory instruments and equipment.
Provide assistance to laboratory staff in designing experiments, using instrumentation, data acquisition and analysis,and preparing figures for publication.
Work as a team to provide upkeep of scientific equipment and resources, including reagents, stocks of frozen sells animal samples, including acquisition, documentation, and storage.
Learns new laboratory techniques and procedures
Program and use computers to store, process, and analyze data
Monitor operational procedures in technical environments to ensure conformance to standards
Interpret research or operational data
Record research or operational data
Develop new automated differentiation protocols for iPSC lines to differentiate into disease-relevant cell types like neurons, astrocytes, and microglia
Develop image analysis routines to analyze the effects of disease-associated mutations on cellular phenotypes
Work with staff to provide insight into the effects of ADRD-associated mutations on molecular readouts in cell culture.
Work with staff to characterize genetic pathways for Alzheimer's disease and related dementia (ADRD) using human cell-based models
Work with staff to apply published protocols for cell differentiation to IPSC lines, microscopy, and molecular analysis.
Program, operate, and implement Client methods on liquid handling platforms (Hamilton, Tecan)
Work with staff on performing large-scale iPSC cell culture experiments on liquid handling platforms.
Support other research projects
Assists with performing basic laboratory experiments and procedures
Collaborate with other team members to carry out large-scale cell culture protocols using high throughout robotic systems.
Prepares, organizes, and maintains various lab samples, supplies, and equipment
Maintain laboratory equipment
Minimum Education :
Master's Degree in a Cell Biology, Neurobiology, or Related Discipline
Field of Study : Biology
Biology
Miscellaneous Biology
Biochemical Sciences
Neuroscience
Software : Microsoft PowerPoint
Microsoft PowerPoint
Excel
Microsoft Word
Skills :
Strong scientific communication skills, both oral and written.
Team player in large research institutes.
Minimum of one (1) year of related experience.
Minimum of two (2) years of related experience
Experience with human iPSC culture and automated platforms
Experience in scripting / coding to create, test, and perform new methods in automated cell culture platforms (Basic Venus-Based method scripting for Hamilton robot would be very much appreciated)
Knowledge of proper laboratory disposal methods and procedures
Strong communication skills, both oral and written
Excellent analytical, organizational, and time management skills