Director, Revenue Forecasting and Commercial Performance (North America)

Director Of Revenue Forecasting And Commercial Performance

Rhythm is a global, commercial-stage biopharmaceutical company committed to transforming the lives of patients and their families living with rare neuroendocrine diseases. We develop medicines for previously untreatable or undertreated diseases and provide meaningful support for healthcare providers and patients and their families. We recognize the courage it takes for patients and their caregivers to begin their journey of advocacy to find the answers they need. Their courage inspires us to challenge convention, ask bold questions and seek answers for them. Every day, we strive for excellence through our willingness to adapt, learn, and our tenacity to overcome barriers, together.

Opportunity Overview

Reporting to the Head of Business Insights and Analytics for the North American region, Rhythm Pharmaceuticals is seeking a strategic and experienced Director of Revenue Forecasting and Commercial Performance for our rare disease portfolio. The role is to serve as the primary analytics partner for the region for all aspects of financial performance from revenue to operating expenses. This role is pivotal in developing robust, data-driven forecasts, scenario planning, analyzing commercial performance, providing ongoing P&L visibility to leadership, and supplementing analytics to support the commercial success of IMCIVREE in current and future approved indications. This role will also have a secondary reporting relationship with the Vice President of Financial Planning and Analysis. The ideal candidate will bring deep expertise in pharmaceutical revenue forecasting, finance, P&L reconciliation, analytics, and a strong understanding of rare disease markets, and a collaborative mindset to work across multiple teams including Commercial, Finance, and Medical.

Responsibilities and Duties

Own and lead U.S. and Canadian revenue forecasts for current and future indications and products.

Lead annual, quarterly and rolling forecasts for revenue, patient projections, and product uptake across the U.S. and Canada for Rhythm's approved and future rare disease indications.

Build and refine complex forecast models incorporating epidemiology data, primary and secondary data, market research, and competitive intelligence.

Drive continuous improvements in forecasting methodology, tools, and processes, leveraging advanced simulation models and sensitivity analyses to drive accuracy and stakeholder buy-in.

Present forecast assumptions, risks, and opportunities in well-structured presentations to support alignment and presentation to senior leadership.

Liaise with International organization to ensure general consistency in forecast approach, where appropriate.

Stay current with competitive landscape and emerging market dynamics within rare diseases to inform forecast adjustments.

Support strategic planning, new indication launches, and business development initiatives through scenario modeling and strategic forecasting.

Drive the Financial Performance Management process for North America.

Operating Expense Budgeting & Forecasting.

Deliver financial and operational support for planning, budgeting, accruals, and forecasting activities to the North America region and department leaders on both monthly and quarterly cycles. Ensure active engagement of participants within appropriate timelines and adherence to corporate budget guidance and targets.

Be the subject matter expert of the financial planning tool (Adaptive) for North American team.

Financial Performance Management.

Track and communicate actual results compared to budget and forecast to North America Leadership team, identifying trends and recommending actions to improve results.

Ensure budgetary compliance through actual variance analyses, vendor dashboard reviews, and purchase order review and management.

Development and enhancement of standard financial reports for monthly and quarterly reviews with North America Leadership.

Additional Business Insights and Analytics support.

Supplement Business Insights and Analytics peers to provide visibility on the health of the business and opportunities for execution including performance of spend or investment initiatives to drive revenue.

Develop KPIs and dashboards to interrogate brand performance, and lead monthly performance reviews, highlight salient trends, quantify risks and opportunities, and distill findings to actionable insights.

Develop a detailed & coherent performance narrative that can be leveraged internally & externally.

Develop materials and ad hoc analytics to support quarterly earnings calls, corporate Long-range plan process, Board of Director meetings, and other key internal meetings.

Collaborate with cross-functional teams including Commercial, Finance, Marketing, Market Access, and Medical.

Coordinate, collaborate, and align with the Corporate and International team on all FP&A-related matters.

Qualifications and Skills

Bachelor's degree in quantitative or scientific field (e.g. Biology, Chemistry, Finance, Economics, Statistics, or related field); advanced degree (MBA or MS) strongly preferred.

Minimum of 10 years of experience in forecasting, commercial analytics, or decision support within the pharmaceutical or biotech industry.

Strong technical skills in Excel, forecasting software, and business intelligence tools (e.g., Power BI, Tableau).

Deep understanding of pharmaceutical datasets including claims and distribution data and extracting data from a data warehouse.

Proven ability to communicate complex data insights to diverse stakeholders and executive leadership.

Strong project management and organizational skills with a high attention to detail.

Provide strategic insights to senior leadership through clear presentations that highlight forecast assumptions, risks, and market opportunities.

Ability to travel 10% for local, regional and national Business meetings.

This role is based out of our corporate office in Boston, Massachusetts. Rhythm operates in a hybrid-work model. Candidates applying must be willing and able to be in the Boston office in coordination with their department and business needs. This role may involve some travel.

More about Rhythm :

We are a dynamic and growing global team spanning more than a dozen countries. At Rhythm we are dedicated to transforming the lives of patients living with rare neuroendocrine diseases by rapidly advancing care and precision medicines that address the root cause. Our team is passionate about expanding access to reach more patients and developing novel therapies for other rare neuroendocrine diseases, including congenital hyperinsulinism. At Rhythm our core values are :

We are committed to advancing scientific understanding to improve patients' lives.

We are inspired to tackle tough challenges and have the courage to ask bold questions.

We are eager to learn and adapt.

We believe collaboration and ownership are foundational for our success.

We value the unique contribution each individual brings to furthering our mission.

Rhythm is an equal employment opportunity employer and does not discriminate against any applicant because of race, creed, color, age, national origin, ancestry, religion, gender, sexual orientation, disability, genetic information, veteran status, military status, application for military service, or any other class protected by state or federal law. Headquartered in Boston, Rhythm is proud to have been named one of the Top Places to Work in Massachusetts.