Senior Director, Oncology Small Molecules and Targeted Delivery Pathology Therapeutic Area Lead, Clinical Pharmacology and Safety Sciences

Location

Waltham,

Massachusetts,

United States

Job ID R-229584 Date posted 13 / 08 / 2025

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Introduction to role :

Join our dedicated Research & Development team in Biopharmaceuticals R&D as a Senior Director , Oncology Small Molecules and Targeted Delivery Pathology Therapeutic Area Lead . You will be accountable for the scientific output of Oncology small molecules (including PROTAC) , Antibody Drug Conjugates and Radionuclides for the Global Pathology department , supporting discovery efficacy and safety across these modalities for AstraZeneca. You will be integral to developing and implementing pathology evaluations and strategies, incorporating new safety models, expand ing multimodal analys e s , supporting image analysis and artificial intelligence into the pathology workflows. This is your chance to make a meaningful impact on patients' lives!

Accountabilities :

In this role, you will foster a culture of continuous improvement and scientific curiosity. You will collaborate with the pathology leadership team to integrate pathology findings with biomarker data, multimodal endpoints, non clinical endpoints, and other relevant scientific information. You will demonstrate your extensive knowledge of toxicological pathology in support of drug discovery & development, and you will coach program pathologists . You will develop networks within the company to drive collaborative research and operational innovations . You will also build and influence networks across the pharmaceutical industry, including academic and industrial partners, competitors, and regulatory agencies.

Essential Skills / Experience :

DVM and international (ACVP / ECVP) board certification required. PhD in pathology, toxicology or related disciplines is a plus

10+ years of experience required in the toxicologic pathology area

Significant experience in toxicologic pathology across drug modalities and therapy areas in support of drug development within the pharmaceutical industry

Excellent communication skills and strong scientific track record with publications in high quality journals

Broad cross-species toxicologic pathology expertise with experience of histopathological evaluation and / or peer review

Strong familiarity with complementary data sets (e.g. clinical pathology, Investigative pathology endpoints)

Highly effective written and communication skills with the ability to clearly convey complex pathology data to a wide range of stakeholders

Demonstrated highly developed collaborative working and ability to lead within a matrix organization

Ability to act as an external ambassador and to influence external organisations to enhance the image and reputation of AstraZeneca

Previous managerial experience in pathology with proven ability to lead, mentor, motivate and develop others

In Office Requirement :

When we put unexpected teams in the same room, we unleash bold thinking with the power to inspire life-changing medicines. In-person working gives us the platform we need to connect, work at pace and challenge perceptions. That's why we work, on average, a minimum of three days per week from the office. But that doesn't mean we're not flexible. We balance the expectation of being in the office while respecting individual flexibility. Join us in our unique and ambitious world. This role does not allow for remote or travel constructs.

At AstraZeneca, we follow the science to explore and innovate. We are committed to making a difference by fusing data and technology with the latest scientific innovations to achieve the next wave of breakthroughs. We celebrate our successes and failures along the way, driven by our shared belief in what science can do. We are always learning from those living with diseases and harnessing digital, data science & AI to fast-forward our research. This is an environment where exploration and curiosity thrives. If your passion is science and you want to be part of a team that makes a bigger impact on patients' lives, then there's no better place to be.

Ready to make a meaningful impact? Apply now!

Date Posted

14-Aug-2025

Closing Date

28-Aug-2025

Our mission is to build an inclusive environment where equal employment opportunities are available to all applicants and employees. In furtherance of that mission, we welcome and consider applications from all qualified candidates, regardless of their protected characteristics. If you have a disability or special need that requires accommodation, please complete the corresponding section in the application form.

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