Senior Director, Portfolio and Operations R&D CC and AI COE

Senior Director, Portfolio and Operations

Technology impacts everything we do. Pfizer's digital and 'data first' strategy focuses on implementing impactful and innovative technology solutions across all functions from research to manufacturing. Whether you are digitizing drug discovery and development, identifying solutions, or making our work easier and faster, you will be making a difference to countless lives.

The Senior Director, Portfolio and Operations is a strategic leadership role within Pfizer Digital, responsible for driving portfolio governance, operational excellence, and business operations across the organization.

This position ensures alignment of portfolio initiatives with enterprise priorities, optimizes resource utilization, and enables transparent decision-making. The role also oversees continuous improvement and communications for the R&D Creation Center and AI Center of Excellence, leads Digital-wide Operations Planning, and manages support for the Digital Capital Budget.

Reporting to the VP, Strategic Initiatives and Delivery, the Senior Director leads the Portfolio and Operations team of colleagues and provides horizontal leadership across all lines of business.

The responsibilities include, but are not limited to :

Portfolio Governance & Strategy

Provide strategic oversight of portfolio governance and prioritization to ensure initiatives align with enterprise objectives and deliver maximum value.

Operational Excellence

Drive operational planning and continuous improvement to streamline processes, enhance efficiency, and support organizational goals.

Financial Management

Oversee financial stewardship for portfolio and operations, including capital budget management, forecasting, and performance reporting.

Communications & Stakeholder Engagement

Lead transparent communication strategies and facilitate leadership engagement to ensure alignment and informed decision-making across the organization.

Leadership & Collaboration

Offer cross-functional leadership, fostering collaboration and capability development to enable successful portfolio delivery and operational execution. Lead team of portfolio managers and change management colleagues.

Team Culture

Cultivate an inclusive, high-performance team culture that promotes innovation, accountability, and engagement across all levels of the organization.

How You Will Achieve It

Portfolio Strategy & Governance

• Lead portfolio management team and oversee portfolio prioritization and governance processes, ensuring alignment with enterprise objectives and compliance with governance standards.
• Partner with category leadership and decision-analysis teams to evaluate portfolio performance, risks, and opportunities, enabling data-driven investment decisions.
• Implement processes for portfolio resource management, including dynamic funding and scenario planning to maximize value within budget constraints.

Operational Leadership

Financial Management

Stakeholder Engagement & Communication

Risk Management & Compliance

Leadership & Collaboration

Team Culture

Basic Qualifications :

Preferred Qualifications :

Non-standard Work Schedule, Travel or Environment Requirements :

The annual base salary for this position ranges from $204,700.00 to $341,100.00.

Pfizer compensation structures and benefit packages are aligned based on the location of hire. The United States salary range provided does not apply to Tampa, FL or any location outside of the United States.

Relocation assistance may be available based on business needs and / or eligibility.