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PK/PD Principal Scientist
PK/PD Principal ScientistZoetis • Kalamazoo, MI, United States
PK / PD Principal Scientist

PK / PD Principal Scientist

Zoetis • Kalamazoo, MI, United States
30+ days ago
Job type
  • Full-time
Job description

The Zoetis Veterinary Medicine Research & Development (VMRD) is seeking a talented PK / PD scientist to join our team to discover and develop novel therapeutics for veterinary medicine. The successful candidate will be primarily responsible for designing, conducting, analyzing, and interpreting in vivo PK / PD studies in multiple species in support of projects from early research through late-stage development. This position will require a highly motivated and independent leader who can effectively collaborate with team members across the organization to advance projects. This position will be hired as a hybrid position, with on-site presence at Zoetis VMRD headquarters in Kalamazoo, Michigan required 50% of the time.

POSITION RESPONSIBILITIES :

  • Independently design, conduct and analyze in vivo PK / PD, PK and TK studies in multiple veterinary species, including writing study protocols and reports.
  • Provide PK and PK / PD modeling and simulation to help select lead candidates and optimize dose regimens.
  • Collaborate with bioanalytical team to understand suitability of analytical assays and forecast analytical requirements for projects.
  • Lead development of scientific strategy across therapeutic areas with a focus on mechanistic platforms / biomarkers to aid in translation, measurement of target engagement, and dose regimen predictions.
  • Work collaboratively and communicate effectively with multidisciplinary teams to design and prosecute studies in line with the strategic direction of the project.
  • Present research results to scientific teams, management, and regulatory agencies.
  • Write sections of regulatory submissions, respond to inquiries from regulatory agencies, and maintain knowledge of regulatory guidance documents.

REQUIRED EDUCATION AND EXPERIENCE :

  • Ph.D in pharmacology, biochemistry, or related field with 4 or more years of relevant pharmaceutical development experience.
  • Proven ability to design, analyze and interpret in vivo PK and PK / PD studies. Experience with biotherapeutics (protein therapeutics) is highly desirable.
  • Skilled in the used of PK and PK / PD analysis software such as WinNonlin, Monolix or Watson.
  • Must have excellent verbal & written communication skills.
  • Self-starter, able to prioritize work and work efficiently with minimal supervision.
  • DESIRED SKILLS :

  • Working knowledge of bioanalytical methodology.
  • Knowledge of ADA assays and assessment of immunogenicity of biotherapeutics.
  • Experience in PK / PD modeling and simulation such as PBPK, QSP or population PK modeling using NONMEM, R, or related software.
  • Experience interacting with regulatory agencies.
  • Experience conducting GLP studies.
  • Full time Regular Colleague

    Any unsolicited resumes sent to Zoetis from a third party, such as an Agency recruiter, including unsolicited resumes sent to a Zoetis mailing address, fax machine or email address, directly to Zoetis employees, or to Zoetis resume database will be considered Zoetis property. Zoetis will NOT pay a fee for any placement resulting from the receipt of an unsolicited resume.

    Zoetis will consider any candidate for whom an Agency has submitted an unsolicited resume to have been referred by the Agency free of any charges or fees. This includes any Agency that is an approved / engaged vendor but does not have the appropriate approvals to be engaged on a search.

    Zoetis is committed to equal opportunity in the terms and conditions of employment for all employees and job applicants without regard to race, color, religion, sex, sexual orientation, age, gender identity or gender expression, national origin, disability or veteran status or any other protected classification. Disabled individuals are given an equal opportunity to use our online application system. We offer reasonable accommodations as an alternative if requested by an individual with a disability. Please contact Zoetis Colleague Services at zoetiscolleagueservices@zoetis.com to request an accommodation. Zoetis also complies with all applicable national, state and local laws governing nondiscrimination in employment as well as employment eligibility verification requirements of the Immigration and Nationality Act. All applicants must possess or obtain authorization to work in the US for Zoetis. Zoetis retains sole and exclusive discretion to pursue sponsorship for the acquisition or maintenance of nonimmigrant status and employment eligibility, considering factors such as availability of qualified US workers. Individuals requiring sponsorship must disclose this fact. Please note that Zoetis seeks information related to job applications from candidates for jobs in the U.S. solely via the following : (1) our company website at www.Zoetis.com / careers site, or (2) via email to / from addresses using only the Zoetis domain of "@zoetis.com". In addition, Zoetis does not use Google Hangout for any recruitment related activities. Any solicitation or request for information related to job applications with Zoetis via any other means and / or utilizing email addresses with any other domain should be disregarded. In addition, Zoetis will never ask candidates to make any type of personal financial investment related to gaining employment with Zoetis.

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    Principal Scientist • Kalamazoo, MI, United States

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