Senior Bioinformatics Software Engineer

Senior Bioinformatics Software Engineer

Location : Remote (CST Hours) -TX

Duration : Full-Time

About BigRio :

BigRio is a remote-based, technology consulting firm with headquarters in Boston, MA. We deliver software solutions ranging from custom development and software implementation to data analytics and machine learning / AI integrations. As a one-stop shop, we attract clients from a variety of industries due to our proven ability to deliver cutting-edge, cost-effective software solutions.

Position Summary :

The Senior Bioinformatics (BI) Software Engineer plays a critical technical role in the design, development, and maintenance of scalable and efficient software solutions for bioinformatics pipelines. This position requires close collaboration with cross-functional teams to deliver data-driven software solutions that align with business objectives.

Key Responsibilities :

• BI Development : Build and maintain reliable software solutions using diverse technologies and databases to meet business requirements.
• Data Modeling : Develop and refine data models to ensure computational algorithm performance and integrity, particularly in areas like genome assembly, mapping, variant calling, and annotation.
• ETL Processes : Design and enhance ETL processes to extract, transform, and load data efficiently, often through API-based integrations.
• Query Optimization : Optimize SQL queries and database performance. Participate in schema design and review processes to maintain high performance and scalability.
• Dashboard & Report Creation : Create interactive dashboards and automated reports using tools like Azure Pipelines, Power Automate, and Nextflow to support data-driven decision-making.
• Collaboration : Work closely with stakeholders, such as analysts, clinicians, lab staff, and developers, to understand needs and deliver timely software solutions.
• Data Integration : Integrate diverse data sources, ensuring accuracy and reliability while minimizing code debt and maintaining system flexibility.
• Quality Assurance : Perform rigorous testing and automate test suites (e.g., with pytest, doctest, Azure Pipelines) to ensure software quality and stability.
• Documentation & Maintenance : Produce clear, comprehensive documentation including inline code comments, wikis, READMEs, and trace mappings to ensure ease of use and maintainability.

Qualifications :

Technical Skills :