Senior Scientist - Antibody Discovery

SystImmune is a leading and well-funded clinical-stage biopharmaceutical company located in Redmond, WA and Princeton, NJ.

It specializes in developing innovative cancer treatments using its established drug development platforms, focusing on bi-specific, multi-specific antibodies, and antibody-drug conjugates (ADCs).

SystImmune has multiple assets in various stages of clinical trials for solid tumor and hematologic indications.

Alongside ongoing clinical trials.

SystImmune has a robust preclinical pipeline of potential cancer therapeutics in the discover and IND-enabling stages, representing cutting-edge biologics development.

We offer an opportunity for you to learn and grow while making significant contributions to the company's success.

We are seeking a highly skilled and motivated Senior Scientist to join our Antibody Discovery Group.

The successful candidate will play a critical role in advancing our antibody discovery efforts through various techniques, including target analysis, immunogen design, B-cell sorting, flow cytometry, ELISA, and yeast library screening.

This position offers an exciting opportunity to work in a dynamic and innovative environment focused on the development of novel therapeutic antibodies.

Responsibilities :

• Perform in-depth analysis of potential targets, including clinical landscape, biology, protein structure, and literature review.
• Design and execute antibody discovery campaigns from immunization to lead delivery.
• Perform high throughput sorting to isolate specific  B cell  populations.
• Design, execute, and analyze FACS experiments to validate and characterize antibodies.
• Develop, optimize, and perform assays (ELISA, BLI,  flow cytometry ) for antibody screening and specificity testing.
• Conduct yeast display library screening to identify and analyze antibody candidates.
• Analyze and compare BCR sequences and immune repertoires.
• Analyze experimental data and prepare detailed reports and presentations.
• Work with cross-functional teams and contribute to project planning and strategy.
• Maintain accurate records, ensure safety compliance, and contribute to lab organization.

Qualifications :

Technical Skills :

Soft Skills :

Work Environment :

Physical Demands :

Compensation and Benefits :

SystImmune offers a comprehensive benefits package including :

We welcome diverse talent and encourage all qualified applicants to apply.