Sr. Medical Director

Sr. Medical Director

Location : Austin, TX (100% Onsite M-F)

Employment type : Full-time, Direct-Hire / Perm

Summary

A leading clinical research organization is seeking an experienced Senior Medical Director (SMD) to provide strategic medical leadership and serve as Principal Investigator (PI) or Sub-Investigator (Sub-I) across multiple therapeutic areas. This role is ideal for a research-experienced physician skilled in adult chronic disease management who thrives in a dynamic, innovative environment.

The SMD will guide clinical trial execution, ensure participant safety and regulatory compliance, collaborate with operational leaders, mentor junior investigators, and support strategic growth through partnerships and community engagement. This position offers the opportunity to drive high-quality research and contribute to the advancement of cutting-edge therapies.

Essential Duties & Responsibilities

Clinical & Research Leadership

• Serve as PI / Sub-I on clinical trials conducted by the research center, including decentralized trials as needed.
• Ensure the conduct of clinical trials aligns with GCP / HSP guidelines , prioritizing participant safety and data integrity.
• Lead medical oversight for ongoing trials, including review of safety data, eligibility, and protocol adherence.
• Review protocols and study materials; assess clinical and operational feasibility of studies.
• Provide therapeutic and protocol-specific training to project teams and investigators.
• Collaborate with feasibility, operations, regulatory, and data management teams to support high-quality trial execution.
• Participate in medical review of recruitment and enrollment strategies.

Strategic & Organizational Contributions

Compliance & Professional Standards

Supervisory Responsibilities

Qualifications

Education & Experience