Senior Scientist / Principal Scientist, DMPK

Senior Scientist / Principal Scientist, DMPK Tenvie is a biotechnology company committed to engineering small molecules that transform the treatment of neurological diseases.

The company’s foundation is purpose-built with a diverse portfolio of small molecules and a proven team of CNS drug developers to rapidly deliver multiple clinical assets.

Tenvie is advancing a pipeline of therapeutics focused on treating neurological, cardiometabolic, and ophthalmic diseases.

Its portfolio of wholly owned, highly brain-penetrant, and precision-designed peripherally restricted small molecules address three key drivers of disease :

• resolving inflammation, rescuing metabolic dysfunction, and restoring lysosomal function.
• The company’s most advanced programs target NLRP3 and SARM1, with additional programs in preclinical development.
• We are looking for a highly motivated and skilled DMPK Scientist with expertise in small molecule drug discovery and early development.
• Reporting to the Senior Director, DMPK & Clinical Pharmacology, this role will represent the DMPK function on projects, guiding and implementing strategies and enabling timely data-driven decision-making throughout the life cycle of small molecule therapeutics.  Key deliverables are human PK and efficacious dose predictions and clinical risk assessment based on translating in vitro and nonclinical data.  This is an excellent opportunity to join a biotech company with groundbreaking work in the field.  This role is onsite.

JOB RESPONSIBILITIES :