Talent.com
Data Scientist / Senior Data Scientist, Statistical Genetics
Data Scientist / Senior Data Scientist, Statistical GeneticsCalicolabs • South San Francisco, California, United States
Data Scientist / Senior Data Scientist, Statistical Genetics

Data Scientist / Senior Data Scientist, Statistical Genetics

Calicolabs • South San Francisco, California, United States
30+ days ago
Job type
  • Full-time
Job description

Who We Are :

Calico (Calico Life Sciences LLC) is an Alphabet-founded research and development company whose mission is to harness advanced technologies and model systems to increase our understanding of the biology that controls human aging. Calico will use that knowledge to devise interventions that enable people to lead longer and healthier lives. Calico’s highly innovative technology labs, its commitment to curiosity-driven discovery science and, with academic and industry partners, its vibrant drug-development pipeline, together create an inspiring and exciting place to catalyze and enable medical breakthroughs.

Position Description :

Calico is seeking a Data Scientist / Senior Data Scientist to join the statistical genetics team within the Computational Sciences group. In this position, you will develop and apply cutting-edge computational methods to analyze unique biobank-scale datasets (e.g. UK Biobank ) to identify potential drug targets for age-related disease. Two major areas of focus will be analysis of longitudinal datasets to identify factors modulating the trajectory of age-related decline and the analysis of high-dimensional phenotypes. The successful candidate will join a vibrant research community and work closely with internal and external scientific collaborators and will be expected to contribute to the design of target discovery or validation efforts.

Position Responsibilities :

  • Develop and apply computational methods suitable for biobank-scale complex or high-dimensional phenotypic datasets from both public and proprietary data sources
  • Conceive, design, and execute studies to interrogate the genetic basis of age-related complex traits and of aging trajectories in large human cohorts
  • Integrate multiple data sources (e.g. clinical data, genetics, ‘omics) to develop therapeutic hypotheses for age-related disease
  • Contribute to software and / or workflows for the analysis of cohort data across multiple research projects and development programs
  • Collaborate with and communicate findings effectively to researchers from a broad range of scientific backgrounds, both internally and externally

Position Requirements :

  • Ph.D. in genetics, statistics, statistical genetics, computational biology, or equivalent
  • Track record of developing and applying new computational and statistical methods tailored to analyzing novel datasets
  • Experience with the statistical genetic toolkit for complex traits (e.g. GWAS, gene burden tests, statistical finemapping, LD score regression, eQTL / pQTL mapping, colocalization, polygenic risk scores, Mendelian randomization), including methods for ancestrally diverse populations
  • Experience with analyzing large, high-dimensional clinical and / or molecular datasets (for example, imaging, genomics and other ‘omics, longitudinal data)
  • Familiarity with large human cohort studies (e.g. UK Biobank, FinnGen, All of Us)
  • Strong coding skills in Python and / or R, including experience developing software and / or workflows that can be readily used by others
  • Strong interpersonal, written, and verbal communication skills, including collaborating with stakeholders from different scientific disciplines
  • Must be able to work onsite at least 4 days a week
  • The estimated base salary range for this role is $120,000 - $185,000. Actual pay will be based on a number of factors including experience and qualifications. This position is also eligible for two annual cash bonuses.

    Create a job alert for this search

    Senior Data Scientist • South San Francisco, California, United States

    Related jobs
    Senior Data Scientist - AI Biology Data Pipelines

    Senior Data Scientist - AI Biology Data Pipelines

    The Chan Zuckerberg Biohub, Inc. • Redwood City, CA, United States
    Full-time
    A leading research organization in Redwood City is seeking a Senior Data Scientist to develop AI-ready datasets that drive scientific innovation. The ideal candidate will have over 10 years experien...Show more
    Last updated: 5 days ago • Promoted
    Senior Data Scientist, Experimentation

    Senior Data Scientist, Experimentation

    Robinhood • Menlo Park, CA, United States
    Full-time
    Join us in building the future of finance.Our mission is to democratize finance for all.An estimated $124 trillion of assets will be inherited by younger generations in the next two decades – the l...Show more
    Last updated: 30+ days ago • Promoted
    Senior Data Scientist, Guest Discovery & Personalization

    Senior Data Scientist, Guest Discovery & Personalization

    Traveltechessentialist • San Francisco, CA, United States
    Full-time
    A leading travel technology firm is seeking a Senior Staff Data Scientist to join their Guest Data Science team.This remote eligible role focuses on leveraging AI and causal inference to enhance gu...Show more
    Last updated: 3 days ago • Promoted
    Senior Data Scientist, Decisions

    Senior Data Scientist, Decisions

    Truebill • San Francisco, CA, United States
    Full-time
    San Francisco, CA, Washington, D.The ideal candidate is interested in working from any of our offices (Silver Spring, NYC, SF, Miami, Denver) 1-2x per week. Rocket Money’s mission is to meaningfully...Show more
    Last updated: 15 days ago • Promoted
    Senior Data Scientist, Analytics

    Senior Data Scientist, Analytics

    Discord • San Francisco, CA, United States
    Full-time
    Discord is used by over 200 million people every month for many different reasons, but there’s one thing that nearly everyone does on our platform : . Over 90% of our users play games, spending a comb...Show more
    Last updated: 30+ days ago • Promoted
    Senior Data Scientist

    Senior Data Scientist

    Adobe • San Francisco, CA, United States
    Full-time
    Senior Data Scientist to partner with the Creative Product Marketing team.Analyze product usage patterns and customer journeys to uncover behavioral insights related to acquisition and retention—tr...Show more
    Last updated: 30+ days ago • Promoted
    Data Scientist / Senior Data Scientist, Statistical Genetics

    Data Scientist / Senior Data Scientist, Statistical Genetics

    Calico LLC • San Francisco, CA, United States
    Full-time
    We’re explorers, optimists, scientists, engineers, inventors, technologists, drug developers and more, working together to make a difference in peoples’ lives. We love science and have the sense of ...Show more
    Last updated: 30+ days ago • Promoted
    Senior Data Scientist

    Senior Data Scientist

    EchoTwin AI, Inc. • San Francisco, CA, United States
    Full-time
    EchoTwin AI is pioneering AI-driven infrastructure intelligence, redefining how cities are managed.Powered by a proprietary visual intelligence engine with full spatial reasoning, EchoTwin transfor...Show more
    Last updated: 15 days ago • Promoted
    Senior Data Scientist, Decisions -Loyalty & Partnerships

    Senior Data Scientist, Decisions -Loyalty & Partnerships

    Lyft • San Francisco, CA, United States
    Full-time +1
    Senior Data Scientist, Decisions, New Product Development.Senior Data Scientist, Decisions, New Product Development.Senior Data Scientist, Decisions, New Product Development.Senior Data Scientist, ...Show more
    Last updated: 30+ days ago • Promoted
    Senior Data Scientist, Growth Analytics

    Senior Data Scientist, Growth Analytics

    Airwallex • San Francisco, CA, United States
    Full-time
    Airwallex is the only unified payments and financial platform for global businesses.Powered by our unique combination of proprietary infrastructure and software, we empower over 150,000 businesses ...Show more
    Last updated: 30+ days ago • Promoted
    Senior Data Scientist

    Senior Data Scientist

    Gladly • San Francisco, CA, United States
    Full-time
    Uniquely powered by Customer AI, Gladly is the only CX platform that puts the customer—not tickets—at the center of every conversation. Trusted by the world’s most customer‑centric brands, including...Show more
    Last updated: 30+ days ago • Promoted
    Senior Data Scientist

    Senior Data Scientist

    Proximity Works • San Francisco, CA, United States
    Full-time
    We’re seeking a highly skilled, execution-focused.This role demands hands-on expertise in building, deploying, and optimizing machine learning models at scale, while working with big data technolog...Show more
    Last updated: 30+ days ago • Promoted
    Senior Data Scientist, Growth Product

    Senior Data Scientist, Growth Product

    Block • San Francisco, California, USA
    Full-time
    Block is one company built from many blocks all united by the same purpose of economic empowerment.The blocks that form our foundational teams People Finance Counsel Hardware Information Security ...Show more
    Last updated: 1 day ago • Promoted
    Senior / Staff Scientist, Data Science

    Senior / Staff Scientist, Data Science

    MedTech Innovator • Berkeley, CA, United States
    Full-time
    Glyphic Biotechnologies is pursuing the protein revolution.We are developing a massively parallel, single-molecule proteome sequencing platform to transform life science discovery.M from venture pa...Show more
    Last updated: 30+ days ago • Promoted
    Senior Data Scientist, Growth

    Senior Data Scientist, Growth

    Grammarly • San Francisco, CA, United States
    Full-time
    Grammarly offers a dynamic hybrid working model for this role.This flexible approach gives team members the best of both worlds : plenty of focus time along with in-person collaboration that helps f...Show more
    Last updated: 30+ days ago • Promoted
    Senior Data Scientist – GenAI

    Senior Data Scientist – GenAI

    Liberate • San Francisco, CA, United States
    Full-time
    Liberate is reimagining how the $2.By starting with voice, the most valuable and complex channel in insurance, the company proved that even the hardest problems can be automated.Now expanding into ...Show more
    Last updated: 28 days ago • Promoted
    Senior Data Scientist Generative AI

    Senior Data Scientist Generative AI

    Roblox • San Mateo, California, USA
    Full-time
    WHY DATA SCIENCE & ANALYTICS.The Data Science & Analytics organizations mission is to increase our speed frequency and acumen in making decisions at scale by instilling a data-influenced ap...Show more
    Last updated: 3 days ago • Promoted
    Senior Data Scientist, Growth

    Senior Data Scientist, Growth

    Headway • San Francisco, CA, United States
    Full-time
    New York, New York, United States; San Francisco, California, United States; Seattle, Washington, United States.Headway’s mission is a big one – to build a new mental health care system everyone ca...Show more
    Last updated: 9 days ago • Promoted