PK/PD Module expert: Translational / Clinical Pharmacology Decision-MakerMercor • Jackson, Tennessee, US
PK / PD Module expert : Translational / Clinical Pharmacology Decision-Maker
Mercor • Jackson, Tennessee, US
19 hours ago
Job type
- Full-time
- Remote
Job descriptionWho we’re looking for Has owned FIH starting dose, SAD / MAD design, and Phase 2 dose selection for multiple assets. - Participated in governance or review boards, defending dose / exposure rationale in front of senior leadership or regulators. - Demonstrates ability to balance nonclinical → clinical translation : tox, PK, PD, potency, and MoA. - Can articulate the real decision calculus behind dose selection (safety, pharmacology, speed-to-proof). - Capable of turning narrative judgment into explicit decision rules and rubrics for AI training and evaluation. ### Experience level ~10+ years in major biopharma or biotech (e.g., Lilly, Roche, AbbVie, Amgen, Novartis, GSK, Regeneron, Vertex, Incyte, Gilead) or in specialized translational pharmacology consulting. - Has personally led FIH dose and / or SAD / MAD escalation for ≥2–3 assets. - Proven governance experience : IND sign-off, dose justification memos, exposure–response presentations. - CV or track record includes statements like _“led clinical pharmacology strategy and FIH dose selection”_ or _“accountable for exposure–response in Phase 1 / 2.”_ - Avoid pure modeling profiles; the ideal expert has decision accountability , not just analytical skill. ### Expectations Write “golden” FIH dose rationales and escalation strategies for representative programs. - Encode the decision heuristics and trade-offs used by senior translational leaders into structured guidance and rubrics. - Surface unwritten decision rules — when and why experienced teams override model-based recommendations. Inputs given : Representative drug programs or data packets (GLP tox summaries, PK / PD tables, potency & MoA context). - Target prompts for translational decision-making (e.g., _“Recommend FIH dose and escalation strategy given these data”_). Expected outputs : Golden Decision Memos : exemplar dose justification memos that reflect the level of reasoning and format expected from top-tier translational pharmacologists. - Decision Rubrics : scoring guides capturing acceptable vs. unsafe dose rationales, missed edge cases, or failure modes. - Meta-Layer Commentary : short narrative explaining unspoken heuristics — how senior teams weigh risk tolerance, potency data, or tox uncertainty.
The client is seeking an external expert who brings a
- decision-maker’s mindset
- — someone who has personally driven translational pharmacology choices under governance and uncertainty.
###
Create a job alert for this search
Clinical Pharmacology • Jackson, Tennessee, US
Related jobs
We are hiring for a Physical Therapist.At Deaconess HomeCare, a part of LHC Group, we embrace a culture of caring, belonging, and trust and enjoy the meaningful connections that come from it : for t...Show more
Earn up to $15 / hour + performance bonuses.Outlier, a platform owned and operated by Scale AI, is looking for.If you're passionate about improving models and excited by the future of AI, this is you...Show more Earn up to $15 / hour + performance bonuses.Outlier, a platform owned and operated by Scale AI, is looking for.If you're passionate about improving models and excited by the future of AI, this is you...Show more 
CDL-A Flatbed Independent Contractor Truck Drivers – Owner Operators and Lease Purchase Program!.CRST The Transportation Solution Inc.
CDL-A truck drivers the opportunity to take control of their ca...Show more Earn up to $15 / hour + performance bonuses.Outlier, a platform owned and operated by Scale AI, is looking for.If you're passionate about improving models and excited by the future of AI, this is you...Show more 
Family Medicine physician job in Tennessee : Selmer, Tennessee, offers physicians a rare blend of close-knit community and professional opportunity.
With a population that values personalized, long-...Show more Mercor is seeking • •native Mandarin speakers • • who can read / write in • •Traditional Chinese • • and are also • •medical professionals • • based in Taiwan.
This role combines your • •clinical expertise • • wi...Show more This person complements the client’s “Translational / Clinical Pharmacology Decision-Maker” team by grounding dose selection and exposure–response analysis in • •quantitative structure and parameter...Show more 
Long Term Acute Care RNs (LTAC RNs) provide quality patient care during the patient assessment, intervention, and evaluation process.
LTAC RNs collaborate with all members of a patient's healthc...Show more CRST The Transportation Solution Inc.We are looking for Experienced CDL A Team Truck Drivers to Haul Dedicated freight all over the US.
CDL A Teams can make $125,000 to $135,000 a year per driver.Gu...Show more 
Adoration Home Health and Hospice.Adoration Home Health and Hospice.Home Health PT to join our team in.Our Home Health PTs provide expert, patient-centered care.
If you're ready to work in a support...Show more
Occupational Therapist Career Opportunity Your Calling, Close to Home and Heart Are you in pursuit of a career that's more than a job, one that aligns with your heart and community? We believe...Show more
AlliedTravelCareers is working with CompHealth to find a qualified Physical Therapist (PT) in Selmer, Tennessee, 38375!.When it comes to finding the perfect locums assignment, sometimes it is all a...Show more
You have what it takes : a competitive drive coupled with exceptional sales ability.In this role, you will be responsible for implementing the sales plan by delivering proficient sales presentations...Show more
Internal Medicine physician job in Tennessee : .Medrina is a large, physician-owned practice that has been a national group for over 13+ years.
As a regional leader growing nationwide, we are current...Show more AlliedTravelCareers is working with Fusion Medical Staffing to find a qualified Physical Therapist (PT) in Henderson, Tennessee, 38340!.
Travel Physical Therapist (PT).Facility in Henderson, Tenness...Show more 
Call us at (877) 838-0380 or Apply Online Below!.Regional CDL-A Truck Driver - Drive With Averitt and Enjoy Real Rewards.
Are you ready for a regional CDL-A truck driving career with great pay, cons...Show more
Pathologist Assistant Opening at a laboratory that provides comprehensive anatomic, clinical and molecular pathology services.
This laboratory specializes in.Also, this laboratory is fully certified...Show more
PT - Physical Therapist
Deaconess HomeCare • Selmer, TN, US
Full-time
Last updated: 30+ days ago • Promoted
Content Editor - Flexible
Outlier • Jackson, TN, United States
Full-time
Last updated: 1 day ago • Promoted
Remote Content QA Reviewer
Outlier • Jackson, TN, United States
Remote
Full-time
Last updated: 1 day ago • Promoted
CDL-A Flatbed Lease Purchase Driver in Milan, TN
AllTruckJobs • Milan, TN, US
Full-time
Last updated: 1 day ago • Promoted
Remote AI Content Reviewer
Outlier • Jackson, TN, United States
Remote
Full-time
Last updated: 1 day ago • Promoted
Family Medicine
CompHealth • Selmer, Tennessee, US
Full-time
Last updated: 30+ days ago • Promoted
Bilingual Traditional Chinese Medical Expert
Mercor • Jackson, Tennessee, US
Remote
Full-time
Last updated: 19 hours ago • Promoted • New!
PK / PD Modeling / Pharmacometrics Lead
Mercor • Jackson, Tennessee, US
Remote
Part-time
Last updated: 19 hours ago • Promoted • New!
Travel LTAC RN in Jackson, Tennessee
Gifted Healthcare • Henderson, TN, US
Full-time
Last updated: 30+ days ago • Promoted
CDL-A Refrigerated Team Truck Driver in Milan, TN
AllTruckJobs • Milan, TN, US
Full-time
Last updated: 1 day ago • Promoted
Physical Therapist / PRN
BrightSpring Health Services • Henderson, TN, United States
Full-time
Last updated: 30+ days ago • Promoted
Occupational Therapist - Home Care - Part-Time...
Fairlawn Rehabilitation Hospital • Henderson, TN, Chester County, TN; Tennessee, US
Full-time +1
Last updated: 14 hours ago • Promoted • New!
Travel Physical Therapist (PT) - $1,820 to $3,000 per week in Selmer, TN
AlliedTravelCareers • Selmer, TN, US
Full-time
Last updated: 30+ days ago • Promoted
Immunology Sales Specialist
Syneos Health / inVentiv Health Commercial LLC • Jackson, TN, United States
Full-time
Last updated: 28 days ago • Promoted
Internal Medicine
Medrina • Jackson, Tennessee, US
Full-time
Last updated: 30+ days ago • Promoted
Travel Physical Therapist (PT) - $1,460 to $1,759 per week in Henderson, TN
AlliedTravelCareers • Henderson, TN, US
Full-time
Last updated: 30+ days ago • Promoted
CDL-A Regional Truck Driver - No Touch Freight - Great Pay and Home Time
Averitt • Henderson, TN
Full-time
Last updated: 30+ days ago • Promoted
Pathologist Assistant OR PA ASCP on Day Shift
KA Recruiting Inc. • Jackson, TN, US
Full-time +1
Last updated: 30+ days ago • Promoted