Director, Product Management- Biopharma

Director, Product Management- Biopharma page is loaded## Director, Product Management- Biopharmalocations : Palo Alto, CAtime type : Full timeposted on : Posted Yesterdayjob requisition id : R-100061

• Company Description
• Guardant Health is a leading precision oncology company focused on guarding wellness and giving every person more time free from cancer. Founded in 2012, Guardant is transforming patient care and accelerating new cancer therapies by providing critical insights into what drives disease through its advanced blood and tissue tests, real-world data and AI analytics. Guardant tests help improve outcomes across all stages of care, including screening to find cancer early, monitoring for recurrence in early-stage cancer, and treatment selection for patients with advanced cancer. For more information, visitand follow the company on,and.
• About the Product Department
• Our Oncology Product team is responsible for the strategy and lifecycle management of our oncology portfolio, and is comprised of two core areas :
• Assay Products
• : Liquid and tissue-based diagnostics for therapy selection and disease monitoring
• Digital Products
• : External-facing digital / data solutions and internal infrastructure supporting clinical and commercial operations
• About the Role
• The
• Director, Product Management- Biopharma
• is a leadership position reporting to our Senior Director of Product Management. You would lead the strategy, development, and commercialization of Guardant’s biopharma-focused diagnostics portfolio, ensuring our products are clinically impactful, scientifically rigorous, and aligned with the needs of our biopharma partners. Viable candidates will have deep expertise in oncology diagnostics, and a passion for driving innovation at the intersection of medicine, product strategy, and biopharma collaboration. While not a requirement, this is an ideal opportunity for clinically-trained MDs, PhDs, or MD / PhDs to work at the forefront of oncology diagnostics.
• Key Responsibilities
• Strategic Leadership & Portfolio Management
• Define and execute a comprehensive product strategy aligned with Guardant’s biopharma business objectives and oncology roadmap
• Lead cross-functional teams to design, develop, and deliver best-in-class assay and digital products for therapy selection and disease monitoring
• Translate market insights and partner needs into actionable product plans, identifying unmet needs and prioritizing opportunities
• Biopharma Engagement & Innovation
• Serve as the primary product liaison to the biopharma business unit, ensuring alignment with biomarker-driven trials, companion diagnostics, and regulatory strategies
• Drive co-development partnerships and data generation initiatives to support product innovation and reimbursement
• Monitor emerging trends, technologies, and competitive activity to inform product differentiation and future roadmap
• Clinical Integration & Commercialization
• Ensure products integrate seamlessly into oncology workflows—physician, nurse, and patient—to maximize adoption and usability
• Collaborate with Medical Affairs and Market Access to develop evidence strategies that demonstrate clinical utility and support payer engagement
• Oversee launch planning, sales enablement, and field training to ensure commercial readiness
• Cross-Functional Collaboration
• Partner with R&D, Clinical Development, Regulatory, and Commercial teams to drive execution across the product lifecycle
• Represent Guardant externally with oncologists, healthcare systems, payers, and biopharma stakeholders to refine value propositions and identify unmet needs
• Contribute to publication planning, clinical conference presentations, and scientific communications
• Qualifications
• Required
• A Bachelor’s degree and 15 years of related experience
• or
• 10-12 years with a Master’s degree; 8 years with a PhD;
• or
• 5 years with a PharmD / MD
• 8+ years of experience in product management, medical affairs, or biopharma strategy within oncology diagnostics or precision medicine
• Proven success in launching and scaling diagnostic or healthcare products
• Strong understanding of liquid biopsy, molecular diagnostics, and biomarker-driven oncology
• Preferred
• Master’s and / or advanced scientific degree is highly preferred
• Experience in companion diagnostics, biomarker development, or clinical trial integration
• Familiarity with payer dynamics, evidence generation, and reimbursement strategies
• Exceptional communication, analytical, and leadership skills with the ability to influence across scientific, clinical, and commercial domains
• Hybrid Work Model :
• This section is applicable to onsite employees who are eligible for hybrid work location as specified by management and related policies. Guardant has defined days for in-person / onsite collaboration and work-from-home days for individual-focused time. All U.S. employees who live within 50 miles of a Guardant facility will be required to be onsite on Mondays, Tuesdays, and Thursdays. We have found aligning our scheduled in-office days allows our teams to do the best work and creates the focused thinking time our innovative work requires. At Guardant, our work model has created flexibility for better work-life balance while keeping teams connected to advance our science for our patients.
• The annualized base salary ranges for the primary location and any additional locations are listed below. This range does not include benefits or, if applicable, bonus, commission, or equity. Each candidate’s compensation offer will be based on multiple factors including, but not limited to, geography, experience, education, job-related skills, job duties, and business need.Primary Location : Palo Alto, CAPrimary Location Base Pay Range : $182,700 - $251,250Other US Location(s) Base Pay Range : $155,300 - $213,550If the role is performed in Colorado, the pay range for this job is : $164,400 - $226,150
• Employee may be required to lift routine office supplies and use office equipment. Majority of the work is performed in a desk / office environment; however, there may be exposure to high noise levels, fumes, and biohazard material in the laboratory environment. Ability to sit for extended periods of time.
• Guardant Health is committed to providing reasonable accommodations in our hiring processes for candidates with disabilities, long-term conditions, mental health conditions, or sincerely held religious beliefs. If you need support, please reach out to Peopleteam@guardanthealth.com
• A background screening including criminal history is required for this role. GH will consider qualified applicants with criminal arrest or conviction histories in a manner consistent with applicable law including but not limited to the LA County Fair Chance Policies and the Fair Chance Act (Gov. Code Section 12952).
• Guardant Health is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, or protected veteran status and will not be discriminated against on the basis of disability.
• All your information will be kept confidential according to EEO guidelines.
• To learn more about the information collected when you apply for a position at Guardant Health, Inc. and how it is used, please review our
• Please visit our career page at :

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