Engineer II, Manufacturing Science and Technology

Engineer II, Manufacturing Science and Technology

Sana Biotechnology is growing, and we are hiring new team members who believe in the potential of engineered cells as medicines, who are passionate about delivering the possible to patients, and who lead with the desire to work on novel ideas. As an MSAT Engineer, you will report to the Executive Director of MSAT and support manufacturing of Sana's stem cell-derived pancreatic islet cell program for persons with type 1 diabetes (SC451). In collaboration with the Research team, you will scale, close, and automate the process in preparation for phase 1 clinical manufacturing. You will support technology transfers to the manufacturing site and serve as person-in-plant during manufacturing runs.

What you'll do

• Apply engineering principles to scale-up, close, and automate PSC-based cell therapy manufacturing processes
• Collaborate with Research to learn and document the process, and execute studies in the PD lab
• Support technology transfers and author technical documents including reports, SOPs, master batch records, and work instructions
• Provide onsite support at the CDMO, train manufacturing operators, and oversee process execution
• Review executed batch records, collaborate with QA to close process deviations, analyze manufacturing trends, and recommend improvements
• Support investigations to troubleshoot process execution challenges including RCA
• Engage and influence team members across multidisciplinary teams while prioritizing multiple projects and meeting deadlines
• Drive curiosity, scientific rigor, and problem-solving skills in a fast-paced environment

What we're looking for

4 years of experience with mammalian cell culture, including 1 year in cell therapy

What will separate you from the crowd

Additional information

Our values and culture

About Sana

We believe diversity strengthens us and are committed to an inclusive workplace. We offer comprehensive benefits including health coverage, paid time off, disability insurance, life insurance, financial wellness programs, 401(k), tuition reimbursement, stock purchase plan, and wellness offerings. We are dedicated to a workplace free of discrimination and harassment. To perform this job successfully, you must be able to perform each responsibility satisfactorily, with reasonable accommodations available for individuals with disabilities.

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