VP, Total Rewards, People Operations & Analytics
Dyne Therapeutics is focused on delivering functional improvement for people living with genetically driven neuromuscular diseases. The company is advancing clinical programs for myotonic dystrophy type 1 (DM1) and Duchenne muscular dystrophy (DMD), and preclinical programs for facioscapulohumeral muscular dystrophy (FSHD) and Pompe disease. At Dyne, we are on a mission to deliver functional improvement for individuals, families and communities.
The Vice President of Total Rewards, People Operations & Analytics is Dyne's enterprise owner for Compensation, Benefits, HR Compliance, HR Operations, and HRIS and People Analytics. As a key member of the HR Leadership Team, this leader will develop comprehensive total rewards and recognition programs, operations and analytics strategies that align to Dyne's people philosophy and culture, build scalable programs and infrastructure, and serve as a key advisor to the CHRO and Compensation Committee to ensure Dyne's rewards and people systems are competitive, equitable, compliant, and insight-driven.
This is a strategic and hands-on leadership role that will ensure Dyne is a top employer by offering competitive compensation, meaningful benefits, and seamless people operations that enhance the employee experience.
This role is based in Waltham, MA without the possibility of being remote.
Key Responsibilities
Compensation (executive & broad-based) :
- Own Dyne's global compensation philosophy and frameworks (market positioning, pay mix, salary structures, job architecture, geographic differentials)
- Lead annual compensation planning (merit, promotions, adjustments), short- and long-term incentive design, sales / field comp as applicable, and equity strategy (grant guidelines, refresh cadence, burn rate / share pool stewardship)
- Partner with the CHRO to prepare materials for and present to the Board Compensation Committee; provide external benchmarking, pay-for-performance insights, and risk / compliance guidance
- Maintain competitive market intelligence (surveys, biotech equity practices), and advise on underwater equity, refresh approaches, and executive offers / retention mechanisms
Benefits, Wellbeing & Leaves :
Own strategy and administration of health & welfare plans, retirement, time-off / leave programs, and wellbeing offerings that reflect our patient-centric culture and growth stageLead annual plan design / renewals, vendor management, fiduciary compliance, communications, and required testing / reportingEnsure benefits and wellness programs align to biotech peer standards for attraction / retentionPeople Operations (HR Ops) :
Lead Dyne's People Operations function with a particular focus on ADP Workforce Now (WFN) as our core HRIS / payroll / benefits platform : oversee system configuration, integrations, access control, data flows, maintenance, and upgradesEnsure ADP WFN and integrated modules (HR, payroll, benefits, talent, time & attendance) support process scalability and data integrityStand up or refine processes across the employee lifecycle (hire-to-retire), including onboarding / offboarding, employee records, policy execution, compliance, and multi-state / global payroll in partnership with Legal / FinanceOwn vendor ecosystem (benefits administration, brokers, payroll, HR tech); negotiate SLAs and performanceDeliver operational excellence that improves employee experience while ensuring accuracy, audit readiness, and regulatory complianceDrive continuous innovation and intelligent automation across all HR systems and processes to enhance scalability, efficiency, and data accuracy as Dyne growsPeople Analytics & Workforce Insights :
Build Dyne's people analytics strategy and operating model with data pulled from ADP WFN and integrated sourcesstandardize definitions, data pipelines, secure governance, and self-serve dashboardsProvide recurring, decision-grade insights : headcount planning, hiring funnel analytics, DEI metrics, rewards effectiveness, engagement / retention risk, organization health, and productivityPartner with Finance on workforce planning, scenario modeling, and budget alignmentLeadership & Governance :
Lead and scale the team across Total Rewards, People Ops (especially the ADP domain), and Analytics; establish clear operating rhythms and SLAsServe as thought partner to CHRO / CFO and a credible voice with the Compensation CommitteeEnsure policies and practices are compliant, equitable, and consistent with Dyne's values and patient-first missionEducation and Skills Requirements :
Bachelor's required; MBA / MS HR / Analytics preferredCEP, CCP, CBP, SHRM-SCP / CEBS helpful for depth in comp / benefits and governance15+ years in HR with deep leadership in Total Rewards, specifically global compensation and benefits. Biotech / pharma experience is highly preferredExpert knowledge of executive and broad-based compensation (market pricing, incentive / Equity design, job architecture) and benefits strategy / administrationExperience preparing and presenting to Compensation Committees; strong grasp of governance, disclosure, and regulatory considerationsExperience with benefits administration, program design, vendor management, and employee communication related to health, welfare, and retirement plansWorking familiarity with ADP Workforce Now (or a similar HRIS / Payroll system) is preferred, with the ability to oversee system functionality, vendor partnerships, and process efficiencyPeople analytics fluency : metrics design, dashboarding, data governance, and storytelling to influence senior leadersDyne Therapeutics is an equal opportunity employer and will not discriminate against any employee or applicant on the basis of age, color, disability, gender, national origin, race, religion, sexual orientation, veteran status, or any classification protected by federal, state, or local law.