Senior Scientist 3 - Chemical Research & Development

Overview :

The Senior Scientist 3 - Chemical Research and Development position is directed toward optimization of existing chemical routes and development of alternate chemistry toward key synthetic intermediates and APIs.

Carries out multistep chemical synthesis and product isolation / purification operations in the laboratory, independently or as part of an integrated team.

Chemist utilizes modern analytical tools to determine identity and purity of products made during projects. Communication with clients in regular team meetings;

prepares R&D reports at the conclusion of projects.

Responsibilities :

Carry out multistep organic syntheses, isolation, and purification of targeted products under supervision or direction of a senior member of the team.

• Must possess a basic understanding of modern organic synthesis methodologies.
• The chemist must have a fundamental understanding of modern analytical and spectroscopic techniques and may possess the ability to interpret the corresponding data and spectra.
• Must demonstrate a proficiency to carry out laboratory syntheses and purification techniques on scales ranging from milligrams to several kilograms.
• Require minimal supervision and be able to coordinate project activities and resource usage.
• Demonstrate ability to write comprehensive reports at the conclusion of projects for internal and customer use.
• With manager review, assist in advising clients on key regulatory guidance.
• Work to ensure that a spirit of teamwork and cooperation always exists within the group.
• Conduct laboratory operations in a safe manner. Maintain familiarity with the companys chemical hygiene plan. Exhibit safety awareness and safe work practices.
• Work closely with manufacturing and GMP operations to coordinate project related equipment and activities.
• Maintain a clean, safe laboratory work area.
• This position works with and handles hazardous materials and wastes. Must have the appropriate qualifications to read, understand, apply, and communicate written and verbal information regarding handling and managing hazardous wastes.

Training is required within six months of assuming duty and once a year thereafter. Responsible for recognizing emergency situations concerning hazardous materials and wastes

Qualifications / Skills : :

Organic Chemistry Knowledge : Strong understanding of the Principles of Organic Chemistry / Process Development.

Cross Discipline Knowledge : Higher level of understanding of the principles of cross-functional departments, including analytical chemistry and engineering.

GMP / Regulatory Knowledge : Demonstrated understanding of industrial GMP and practical application to Cambrex programs;

ability to help identify risks for regulatory compliance or violation of site SOP.

Instrumentation : Demonstrated ability to use, train, investigate root cause issues with HPLC, GC, good understanding of MS, uses automated reactors, may have some experience with In-situ reaction monitoring.

Communication : Good written and oral communication skills, ability to communicate with clients without manager supervision.

Problem Solving : Strong demonstration of problem solving, ability to lead investigations.

Time Management : Able to maintain timeline of key activities and use time efficiently; ability to handle projects without supervision, though still requires regular check-in with manager.

Leadership : Regularly seeks to share ideas and learning across the group / site; pushes new initiatives from the ground up.

Technical Documentation and Review : Ability to author and review key technical documents with minimal RFT errors. Can write new SOP with manager assistance, keep current lab notebook while practicing GDP.

External Influence : Ability to lead local project teams and steer clients to desired outcomes; ability to work with management to develop key local laboratory-based initiatives.

Industry Credibility and Rapport : Recognized scientific leader within the Cambrex organization, locally and possibly beginning to extend to other sites.

Operational Excellence : Actively participates in key operational excellence initiatives.

Change Orientation : Active participation and support for implementation of Cambrex System level changes / initiatives.

Qualifications :

Ph.D. in Chemistry or related field with minimum 4 years experience or M.S. in Chemistry or related field with minimum 8 years experience or B.

S. degree in Chemistry or related field with 12 years of experience in lab environment, pharmaceutical experience preferred.

Hands on experience in pharmaceutical / chemical process development. Excellent verbal and written communication / interpersonal skills, organizational skills, and the ability to work in a diverse team environment are essential.

Proficiency with Microsoft software (SharePoint, Word / EXCEL / PowerPoint), and Chemdraw is expected.