Description
Design and execute experiments using adult and iPSC-derived lung epithelial cells to develop functional lung epithelial tissue on 3D printed lung models.
Develop and implement analytic assays (immunocytochemistry, biochemical assays, cell proliferation assays, gene expression analysis) to evaluate lung epithelial tissue formation and maturation on 3D printed lung models.
Develop and implement strategies and analytic assays to evaluate media effects, co-culture techniques, and large-scale culture methods for pulmonary tissue engineering.
Record experimental details and findings in electronic notebook entries, write project reports, and internally present research findings.
Coordinate with supervisor for project directions, experimental planning, and to review results and progress.
Contribute to IP, regulatory filings, and journal publications, if necessary.
Maintain high level of communication with internal cross-functional R&D team, as well as external vendors and consultants.
Perform other duties as assigned.
Minimum Requirements
Doctor of Philosophy (PhD) in Biology, Biomedical Sciences, Tissue Engineering, Bioengineering, or equivalent
Track record of success (publications,products, patents, grants, or fellowships) in a field related to pulmonary biology, iPSC-derived epithelial / endothelial lineages, tissue engineering, and / or culturing cells in novel contexts.
Strong technical experience including imaging techniques (e.g. basic microscopy, confocal imaging, image analysis) and biological analytical assays (e.
g. immunocytochemistry, gene expression analysis, ELISAs, flow cytometry, viability assays, etc)
Minimum one first-author publication in a related or comparable field.
High organizational skills, strong communication skills, adaptability, and independent trouble-shooting capabilities
Preferred Qualifications
Experience in the field of lung development and / or regeneration.
In-depth knowledge of alveolar (AT2, AT1) epithelial cells and biology.
Experience with the operation of bioreactors, microfluidics, scaffolds, and / or other dynamic or large-scale culture systems.
Experience with cell-cell interactions, ECM production, or co-culture techniques
Post-doctoral or industry experience may be beneficial but not required.
While United Therapeutics does not require vaccination for Covid-19 at this time, we strongly encourage all employees and visitors to remain up to date on vaccinations and boosters to protect one another from illness.
Employees working in customer-facing roles must adhere and comply with customers’ credentialing guidelines, which may require vaccination against Covid -19, the influenza virus, and other illnesses that could be harmful to healthcare staff and patients.
United Therapeutics Corporation is an Equal Opportunity / Affirmative Action Employer - EOE Minorities / Females / Protected Veterans / Individuals with Disabilities
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