Senior Director, Technical Operations

About Loyal

Loyal is a clinical‑stage veterinary medicine company developing drugs intended to extend the lifespan and healthspan of dogs. Our mission is to help dogs live longer, healthier lives. We've already achieved significant milestones on our path to earning FDA approval for the first lifespan extension drug for any species. We have three products in our pipeline and are on track for FDA conditional approval within the next year. Loyal is a well‑funded startup in growth mode. Our team includes scientists, veterinarians, engineers, operators, and creatives. This role will play a key role in supporting our growth strategies.

About The Role

We're seeking an experienced Senior Director, Technical Operations to provide technical leadership across all CMC disciplines as we advance our programs from early development through commercialization — including preparations for upcoming product launch. This role serves as a cornerstone of our Technical Operations organization, ensuring connectivity, scientific rigor, and technical excellence across process, analytical, and formulation development, manufacturing, and supply. The ideal candidate holds a PhD in Chemical Engineering or a related discipline, brings deep expertise in small molecule and oral solid dosage development, has led early‑stage CMC activities, and possesses a proven track record of launching commercial products. You'll integrate and drive the technical aspects of CMC strategy — ensuring robust science, risk‑based decision‑making, and manufacturing readiness that support Loyal's mission and future launches. This role reports to the Chief Technical Operations Officer and works closely with CMC functional leads and executive leadership.

Responsibilities

• Provide technical leadership and integration across process, analytical, and formulation development, ensuring scientific rigor, data integrity, and seamless progression from early development through commercialization.
• Drive technical connectivity among CMC functions to maintain alignment, consistency, and robust science across all development stages.
• Lead technical risk assessment, mitigation, and decision‑making, ensuring issues are identified, analyzed, and resolved through data‑driven approaches.
• Partner with CMC functional leads and CDMOs to develop and refine scalable, robust, and reproducible processes for drug substance and oral solid dosage drug and finished products.
• Oversee technical readiness for key milestones including IND / IMPD, NDA / MAA, and commercial launch.
• Lead or contribute to CMC sections of regulatory submissions and represent Loyal in technical discussions with regulatory authorities.
• Collaborate closely with Quality, Regulatory, Clinical, and Commercial functions to ensure technical and operational alignment.
• Mentor and guide internal scientists and external partners to uphold a culture of technical excellence and accountability.

About You

Nice to have

Salary

$230,000 – $280,000 per year

Benefits

Equal Opportunity Employer

Loyal is founded and led by a first‑gen female CEO and is proud to be an equal opportunity employer. We do not discriminate against applicants based on gender, race or color, ethnicity or national origin, age, disability, religion, sexual orientation, gender identity or expression, veteran status, or any other applicable characteristics protected by law.

Values

Seniority level

Director

Employment type

Full‑time

Job function

Other

Industries

Technology, Information and Internet

Location

San Francisco, CA

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