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Legend Biotech
Associate Research Scientist IILegend Biotech • undefined, undefined, undefined
Associate Research Scientist II

Associate Research Scientist II

Legend Biotech • undefined, undefined, undefined
30+ days ago
Job type
  • Full-time
Job description

Job Description

Role Overview:

Legend Biotech is a clinical stage biopharmaceutical company focused on the discovery and development of novel cell therapies for oncology, immunology and infectious disease indications. We are currently seeking a talented and motivated candidate to join the R&D cell biology and immunology lab at US site. The successful candidatewill contribute to the company’s efforts to develop next-generation cell therapies in solid tumor malignancies. The successful candidate will have a strong Molecular biology/Cell biology and Immunology background, and expect to work in a collaborative cross-functional team environment, perform experiments, organize and analyze results, communicate effectively and present findings in team meetings.

Major Responsibilities:

  • Assist in developing T cell therapy platform, perform cell-based immunoassays, including ex-vivio antigen specific T cell isolation and expansion, Viral-vector based introduction ofTCRs / CARs into human T cells, multi-color flow cytometry, ELISA, ELISPOT assays
  • Culture and characterize genetically modified human T cells and tumor cells including gene expression and cell functionalities testing
  • Plan and execute in vitro functional assays with T cells according to project goals and timelines.
  • Effectively communicate plans and results in both oral and written form.
  • Ability to work in a highly dynamic collaborative team environment.
  • Other duties as assigned

Qualifications

Experience:

  • > 5 year with or 2-5 year with Industry/academic experience inImmunology/Cell Biology, preferably Immunotherapy.

Key Capabilities, Knowledge, and Skills:

  • Experience with multi-color flow cytometry and data analysis (FACSDiva, FlowJo) required.
  • Experience with primary T cell-based assays preferred.
  • Excellent mammalian cell/tissue culture and sterile technique required.
  • Strong organizational skills and record keeping.
  • Self-motivated and willing to accept temporary responsibilities outside of initial job description.
  • Comfortable in a fast-paced environment and able to adjust workload based upon changing priorities.
  • Excellent interpersonal, verbal and written communication skills are essential in this collaborative work environment.
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