Postdoctoral Fellow - metastasis, sarcoma

Date Posted Thursday, February 15, 2024 Position is with Lab / Branch / Program Name of Hiring Official / Investigator

Job Description

A postdoctoral fellow position is available in the Comparative Oncology Program (COP), CCR, NCI, NIH. The mission of the NCI-COP is to strategically position the canine cancer patient in studies of cancer biology and drug development to improve outcome for both dogs and humans.

The COP is seeking highly motivated and collaborative candidates with a background in molecular biology and / or comparative oncology to use a multiprong experimental approach including in vitro and in vivo modeling.

The successful candidate will investigate mechanisms underlying metastatic progression of human and canine osteosarcoma (OS).

Projects will be supported by the DOG2 initiative (Deciphering the Osteosarcoma Genome of the Dog), a multi-omic approach which leverages the COP’s access to high-quality clinically-annotated canine OS specimens collected during the last 5 years of clinical trial activities in >

400 dogs with OS. Any identified druggable targets, particularly those found to be shared between canine and human patients, will be examined in cell culture studies and preclinical (mouse) models to prioritize the best agents to carry forward into pet dog clinical trials, conducted through our extramural clinical trials consortium, the Comparative Oncology Trials Consortium (COTC).

Qualifications and Job Details

Degree Required or equivalent Job Location Bethesda Appointment Type Training Position (Starting stipend : $65,100, bonuses may apply) Work Schedule Full-time (In-Person) Citizenship US Citizenship not required - (ie, permanent resident, visa)

Required and Preferred Skills

Required Skills

Molecular and cancer cell biology; mouse modeling of cancer; proficient in presentation of data in written and oral formats

Preferred Skills

Experience in cross-species genomics and bioinformatics techniques; sarcoma biology; spatial biology and transcriptomics

About the NCI Center for Cancer Research

The Center for Cancer Research (CCR) is home to nearly 250 basic and clinical research groups located on two campuses just outside of Washington, CCR is part of the National Cancer Institute (NCI) and makes up the largest component of the research effort at the National Institutes of Health (NIH).

Centrally supported by long-term funding and a culture of complete intellectual freedom, CCR scientists are able to pursue the most important and challenging problems in cancer research.

We collaborate with academic and commercial partners and advocacy groups across the world in efforts to prevent, diagnose and treat cancer and HIV / AIDS.

The CCR research portfolio covers the full spectrum of biological and biomedical research. Our work ranges from basic to translational and clinical, and our clinical trials are conducted in the NIH Clinical Center, the world’s largest hospital dedicated to clinical research that offers a robust infrastructure to support CCR’s patients on an estimated 250 open studies.

The success of CCR is grounded in an exceptionally strong discovery research program that provides the foundation for the seamless translation of insights from bench to bedside.

Read more , the of working at CCR and hear from on their CCR experiences.

Bethesda

Bethesda is one of the most highly educated communities in the United States and has a nationally renowned school system.

The city is a thriving suburban center close to Washington, , and home to many restaurants, retailers and a flourishing arts and entertainment district.